Prolonged renal failure secondary to antithymocyte globulin treatment in severe aplastic anemia.

Objective: To report a case of acute renal failure in a patient with severe aplastic anemia after administration of antithymocyte globulin (ATG).

Case Summary: A 41-year-old man diagnosed with severe aplastic anemia was treated with ATG and cyclosporine. After one dose of ATG (3012 mg, 40 mg/kg), the patient developed anuric acute renal failure, with serum creatinine 3.

Interstitial nephritis secondary to bevacizumab treatment in metastatic leiomyosarcoma.

Objective: To report a case of interstitial nephritis associated with the administration of bevacizumab.

Case Summary: A 26-year-old man diagnosed with metastatic rectal leiomyosarcoma was treated with intravenous bevacizumab 5 mg/kg and received a total of 3 doses at 2 week intervals. His creatinine had increased from 1.