Autologous tooth bone graft block compared with advanced platelet-rich fibrin in alveolar ridge preservation: A clinico-radiographic study.

Objectives: To determine the clinico-radiographic efficiency of partially demineralized dentin matrix block (PDDM block), a mixture of PDDM with advanced-platelet-rich fibrin+ (A-PRF+) and injectable platelet-rich fibrin versus A-PRF+ alone in alveolar socket preservation.

Materials And Methods: Sixteen molar teeth indicated for extraction were randomly assigned into two groups. For the test group, sockets were packed with PDDM block and control group, with A-PRF+ plug alone.

A Radiohistographic Analysis of Growth Factor-Mediated Sinus Augmentation in Atrophic Maxillae: A 30-Month Follow-up Study.

A total of 20 atrophic maxillary sinuses were augmented with recombinant human platelet-derived growth factor BB (rhPDGF-BB), alloplast, and bovine xenograft using a direct approach. CBCT imaging was performed at baseline, immediately postoperatively, and at 6 and 30 months postoperatively. A histologic evaluation revealed the bone bridging and bone regenerative efficacy of the graft material.

Augmentation of Peri-implant Keratinized Mucosa Using a Combination of Free Gingival Graft Strip with Xenogeneic Collagen Matrix or Free Gingival Graft Alone: A Randomized Controlled Study.

To evaluate the gain in peri-implant keratinized mucosa (KM) using a combination of a free gingival graft (FGG) strip with a xenogeneic collagen matrix (XCM) and compare it to that of an FGG alone. This randomized controlled clinical study included a total of 30 patients with a minimal amount of peri-implant KM (≤ 1 mm) in the maxillary and mandibular anterior regions (including the premolars). The study population was divided into two groups using a randomization protocol; group A (n = 15) received a combination of FGG strip and XCM, and group B (n = 15) received FGG only to augment the KM.

Advanced platelet rich fibrin demonstrates improved osteogenic induction potential in human periodontal ligament cells, growth factor production and mechanical properties as compared to leukocyte and platelet fibrin and injectable platelet rich fibrin.

Objectives: This cross-sectional invitro research aimed to compare and contrast the macroscopic and microscopic, mechanical and biochemical features of leukocyte-rich platelet-rich fibrin, advanced platelet-rich fibrin, and injectable platelet-rich fibrin.

Materials And Methods: In all, 150 samples were taken from males aged 18 to 25 with good systemic health (n = 50 each for i-PRF, A-PRF, and L-PRF). The samples were assessed for clot length, clot width, membrane length and width.

Clinicoradiographic evaluation of advanced-platelet rich fibrin block (A PRF + i PRF + nanohydroxyapatite) compared to nanohydroxyapatite alone in the management of periodontal intrabony defects.

Background: Several bone grafting formulations have been given clinically acceptable outcomes in treating intrabony defects. Platelet rich fibrin (PRF), an autologous platelet concentrate holds potential to be used for regenerative treatment. The purpose of this study was to evaluate clinical and radiographic outcomes in periodontal intrabony defects treated with advanced-PRF block (A PRF + i PRF + nanohydroxyapatite [nHA]) compared to nHA alone.

Second-Generation Liquid Platelet Concentrates: A Potential Boon for Regenerative Dentistry.

Platelet concentrates have seen significant advancement in the field of biological surgical wound additives. The focus is now on second-generation platelet concentrates, which are completely autologous with no external additives. Unlike other platelet concentrates, liquid or injectable platelet-rich fibrin (i-PRF) is the only one that is obtained in a liquid form.

Efficacy of antimicrobial photodynamic therapy on the tongue surface in the management of halitosis - A real-time polymerase chain reaction analysis.

Aim: To evaluate the additional effect of a single session of antimicrobial photodynamic therapy (aPDT) on the tongue as an adjunct to scaling and root planing (SRP) on most common volatile sulfur-producing microbes such as Porphyromonas gingivalis (Pg), Treponema denticola (Td) and Fusobacterium nucleatum (Fn) on 3rd, 7th and 14th day postoperatively using RT-PCR analysis.

Method And Materials: Twenty-four patients of either sex, presented with moderate to severe malodor, detected by a portable breath checker (Tanita®) were considered for the study and assigned to group A & B. Scaling and root planning was performed in both the groups, followed by photodynamic therapy on the tongue surface in group A.

Second-generation Liquid Platelet Concentrates: A Literature Review.

Liquid or injectable platelet-rich fibrin (PRF) is a second-generation platelet concentrate that is completely autologous and free of external additives, like bovine thrombin and calcium chloride. Additionally, it is the only one to be obtained in a liquid form among the second-generation platelet concentrates. This allows for wide applications such as maximizing injections or mixing with biomaterials such as bone grafts or antibiotics.

Evaluation of Osteoblast Response to the Effect of Injectable Platelet-rich Fibrin Coating on Titanium Disks.

Aim: Biomimetic implant surface coatings can improve osteoblast response and enhance osseointegration. This study aimed to assess the response of osteoblast-like cell line (MG-63) coating of injectable platelet-rich fibrin on titanium discs.

Materials And Methods: Injectable-PRF (i-PRF) was prepared by centrifugation of blood at 700 rpm for 3 minutes without any anti-coagulant in i-PRF tubes.

Immediate Ridge Augmentation Using Autogenous Tooth Root as a Block Graft in a Periodontally Hopeless Extraction Site: A Pilot Study.

The aim of the our study was to assess the efficacy of autogenous tooth root as a block bone graft in reconstructing the vertical and horizontal dimensions at periodontally hopeless extraction sites both clinically and radiographically. A total of 13 patients having a tooth with periodontally hopeless prognosis and indicated for extraction were included in the study. Following atraumatic extraction, the tooth was processed to create a decoronated cementum-free dentin block which was used to augment the extraction socket.

Maxillary Sinus Augmentation Using Hydraulic Pressure by Lateral Approach and Simultaneous Implant Placement: Clinicoradiographic Study.

The purpose of this study was to assess clinically and radiographically efficacy of maxillary sinus augmentation using hydraulic pressure in a lateral approach with immediate implant placement. In a total of 10 patients having less than 4 to 6 mm of subantral bone height, lateral approach sinus membrane elevation procedure was performed using hydraulic pressure with the help of a specialized water lift kit followed by grafting and simultaneous implant placement. Cone beam computed tomography analysis was used to assess the change in subantral bone height from baseline to the 6 months postoperatively.

Utilization of Census Tract-Based Neighborhood Poverty Rates to Predict Non-adherence to Screening Colonoscopy.

Objectives: Efforts to improve colorectal cancer (CRC) screening rates include recognizing predictors of colonoscopy non-adherence and identifying these high-risk patient populations. Past studies have focused on individual-level factors but few have evaluated the influence of neighborhood-level predictors. We sought to assess the effect of census tract-based neighborhood poverty rates on scheduled screening colonoscopy non-adherence.

Biological activation of bone grafts using injectable platelet-rich fibrin.

Platelet-rich fibrin (PRF) is gaining acceptance as a bioactive surgical additive in regenerative dentistry. However, PRF has only been available in gel or membrane form and is not suitable for injection. Recently, however, a liquid, injectable PRF has been introduced.

Titanium particles in tissues from peri-implant mucositis: An exfoliative cytology-based pilot study.

Background: To evaluate the presence of titanium particles in the peri-implant mucosa of unloaded single implants.

Materials And Methods: Forty participants with single unloaded implants were selected. They were divided equally into two groups: Group 1 with mild and Group 2 with moderate-to-severe peri-implant mucositis.

Neutrophil priming: Implications in periodontal disease.

Periodontal disease is a well-regulated response to bacterial infection directed by the inflammatory cells of the host immune system. The host response to injury or insult is implicated to be a vital feature of the majority of periodontal diseases. The excessive activation of neutrophils plays a role in the pathogenesis in diseases such as acute respiratory distress syndrome, rheumatoid arthritis, and periodontitis by contributing to inflammatory tissue injury.

Influence of various factors on patient compliance after periodontal therapy: A pilot study.

Background: Patient compliance is an important predictor of periodontal prognosis, therapy, and maintenance. Limited studies concentrate up on the factors which affect patient compliance. Thus, the aim of the study is to determine the relationship between sociodemographic data, patient's oral health awareness (OHA) and treatment satisfaction (TS) to patient compliance.

An Update on the Protocols and Biologic Actions of Platelet Rich Fibrin in Dentistry.

Platelet rich fibrin (PRF) is a surgical biologic additive that is prepared by manipulation of autologous blood. It has now evolved to become one of the most widely used platelet concentrate in dentistry. It has almost replaced Platelet rich plasma (PRP) for usage owing to its advantages such as being 100% autogenous, easy technique, time and cost effectiveness, superior & prolonged growth factor release.

Titanium Corrosion: Implications For Dental Implants.

Titanium has been considered as one of the most biocompatible metals. Studies testing its corrosion resistance have proposed that the titanium oxide layer formed on the metal surface is lost under certain unavoidable conditions to which it is exposed in the oral environment. This questions its property of corrosion resistance in the oral cavity.

Cortical lamina technique: A therapeutic approach for lateral ridge augmentation using guided bone regeneration.

Background: The present study aimed at evaluating the efficacy of a novel technique, the bone lamina technique, in horizontal ridge augmentation clinically & radiographically using a combination of allogenic cortical shell, particulate xenograft and resorbable collagen membrane.

Material And Methods: Localized horizontal ridge defects, in ten patients (6 male, 4 female), with bucco-palatal ridge width less than 5 mm were included in this study. Localised ridge augmentation was performed using bone lamina technique with mineralised allogenic shell of 1 mm thickness trimmed to the appropriate size using stereo-lithographic models and fixed to the recipient site with stainless steel micro-screws of 1 mm diameter.