Oxidative stress in chronic periodontitis patients with type II diabetes mellitus.

Objective: Oxidative stress (OS) refers to the disequilibrium between free radicals and antioxidant defense mechanisms and is significantly implicated in the pathogenesis of chronic degenerative and inflammatory diseases such as chronic periodontal disease (CP) and diabetes mellitus (DM). This study aimed to evaluate the total antioxidants capacity (TAOC) and total oxidants status (TOS) in the gingival crevicular fluid (GCF) in CP participants with type II DM.

Materials And Methods: A total of 80 participants were allotted into four groups as follows: Group 1: Generalized CP (GCP) without type II DM ( = 20); Group 2: GCP with type II DM ( = 20); Group 3: Type II DM without CP ( = 20); and Group 4: Systemically and periodontally healthy (PH) ( = 20).