Hippocampal volume as a predictor of short-term ECT outcomes in older patients with depression.

Objective: The authors examined the relationship between hippocampal volume and acute electroconvulsive therapy (ECT) outcomes.

Methods: Depression was measured by Montgomery-Asberg Depression Rating Scale (MADRS) scores, and hippocampal volume was assessed by magnetic resonance imaging.

Results: After controlling for baseline MADRS score, larger right-hippocampal volume was associated with higher MADRS scores after an index course of ECT.