Circulatory system in children with localized scleroderma.

The circulatory system was studied in 43 children (ages 3-18 years, mean 10.6 years; 32 girls, 11 boys) suffering from localized cutaneous forms of scleroderma. The following studies were undertaken: general pediatric examination, cardiologic examination including routine electrocardiogram (ECG), 24-h Holter ECG monitoring, echocardiography plus Doppler study, and a treadmill exercise test.

[Echocardiography examinations in children suffering from cutaneous forms of scleroderma].

In 34 children suffering from so called cutaneous forms of scleroderma and in 30 healthy subjects echocardiographic cardiac assessment as well as doppler analysis of mitral valve function was performed. It was found that sclerodermic children suffered more frequently from cardiac valves regurgitation (especially insufficiency of mitral valve). However, these insufficiencies were usually negligible or corresponding to Io.

Premictional volume and contractility of the urinary bladder in patients with systemic sclerosis.

Ultrasonographic measurements of the urinary bladder in 21 women with systemic sclerosis (SSc) revealed abnormal volume of the bladder in about 65% of patients; 6/21 had a smaller bladder and 7/21 had a larger bladder than the controls. The volume of the remaining urine after miction was higher in 7 patients. Fibrosis of the bladder wall leading to a small rigid bladder and ureteral obstruction resulting in a large bladder with low contractility are suggested as phenomena involved in disturbed function of the urinary bladder in SSc patients.

Vitiligo associated with lichen planus. Is there a pathogenetic relationship?

We report the case of a 13-year-old boy with vitiligo who developed lichen planus involving both vitiliginous skin and normally pigmented skin. Biopsy of lichen planus surrounded by a depigmented halo revealed a dermal infiltrate composed of CD3 + T cells and macrophages. The association of these skin diseases may indicate a pathogenetic relationship.

[The circulatory system in children with cutaneous forms of scleroderma. The results of routine as well as 24-hour ECG and physical performance test].

Thirty-four children suffering from so-called cutaneous forms of scleroderma were studied (physical examination, routine and 24-hour ECG, and physical performance test). Physical development was significantly impaired in 5 cases. Congenital heart malformations with left-to-right shunt were detected in 3 children.

[Clinical evaluation of serious forms of acne treated with autovaccine].

In this paper a clinical assessment of the treatment of serious forms of acne vulgaris with the use of autovaccines containing Propionibacterium strains was presented. It was shown that the associative therapy including parallel administration of both autovaccine and the antibiotic is remarkably efficacious.

[Influence of progressive systemic sclerosis on gastric emptying].

Gastric motility was measured with an isotopic method in patients with progressive systemic sclerosis (PSS). Twenty-six women aged 48 +/- 10 yr with PSS were investigated. The duration of PSS prior to the study ranged from 2 to 25 yr.

[Volume of the functioning gallbladder and its emptying in patients with progressive systemic sclerosis].

Unlabelled: The aim of the study was to measure the gallbladder volume (GV) and its emptying after meal stimulus in patients with progressive systemic sclerosis (PSS). 18 women with PSS, aged 49.8 +/- 9.

[Use of Nd:YAG laser for treatment of basal-cell carcinomas and some premalignant conditions].

In 51 patients, 29 female and 22 male of average 61 years old, 94 lesions were treated with Nd: YAG laser; 70 basal-cell carcinomas, 9 superficial basal-cell carcinomas, 12 actinic keratosis and 3 cutaneous horns. Size of changes varied from 7 to 24 mm. Quantity of energy used in laser-therapy was dependent on diagnosis, focus size, location and amounted from 50 to 240 J/cm2.

[Hypersensitivity to allergens from the panels standard I and II in automobile tire manufacturers at Stomil plant].

Dermatological examination and patch tests were done in 114 manufacturers of tires, 78 women and 36 men, mean age 29 years, working in Stomil Plant. Patch tests included 15 substances in panels Standard I and II (excluding rubber components). The study demonstrated hypersensitivity to nickel and formalin (4.

[Epidemiology of contact hypersensitivity to rubber components in manufacturers of automobile tires at the Stomil plant].

Dermatological examination and patch tests with 34 rubber components were carried out in 114 tire manufacturers, 78 women and 36 men aged 29 years on average, with a mean duration of work in the plant 7 years. For correct interpretation of the obtained results patch tests with the same components were done in two control groups that is in 120 healthy subjects and 120 patients with contact dermatitis. Patch tests with proper concentrations of the studied components were evaluated after 48, 72 and 96 hours.

[Evaluation of surgical treatment of keratoacanthoma].

From 1973 to 1988 in the Dermatological Surgery Unit of the 1st Department of Dermatology of the Silesian School of Medicine in Katowice 82 patients were treated surgically for keratoacanthoma. In 76 patients the defect was closed by simple bringing closer the edges or by local plastic surgery, in 6 patients it was covered with free full-thickness skin grafts. The preparations of the excised tumors from various places were examined histologically.

[Evaluation of the results of surgical treatment of granuloma teleangiectodes].

In the clinic of dermatological surgery, I Department of Dermatology Silesian Medical Academy in Katowice 328 patients were treated surgically for granuloma teleangiectodes in the years 1973-1988. Two methods were used: excision of the lesion and curettage with electrocoagulation of the base of the lesion. After excision the wound was closed by approximation of its margins or local plastic procedure (285 cases) and by covering it with a free full-thickness skin graft (3 cases).

[Akne-Mycyna in the local treatment of acne].

Akne-Mycyna, a new preparation for external treatment of acne containing 1% erythromycin, was used in 30 cases of acne: 12 cases of papulo-pustolous acne, 13 with pustulous acne, 5 with acne conglobata. The age of the patients ranged from 16 to 27 years, the mean duration of acne was 3.5 years.

[A case of superficial disseminated actinic porokeratosis treated with an aromatic retinoid].

In 55-year-old woman with a history of 19 years of superficial disseminated actinic porokeratosis Tigason was used in doses from 0.7 to 0.5 mg/kg daily in two courses of therapy lasting about 3 months.

[Uncommon location of basal cell epithelioma].

The authors present three patients with the relatively rare location of basal-cell epithelioma in the axilla. The patients were surgically treated.

[Phencarol in the treatment of allergic dermatoses of various pathological mechanisms].

Phencarol produced in the USSR is an antihistaminic drug highly effective in allergic dermatoses with the pathological mechanism of humoral and cellular type. The best results were obtained in acute allergic dermatoses and in acute recurrences of chronic allergic diseases. In comparative studies with difergan a greater efficiency of phencarol was noted, which was expressed as a higher proportion regression of lesions and more rapid action of the drug.

[Basal cell carcinoma among the cases of Dermatology Clinic I of the Silesian Medical Academy in Katowice].

The authors present their own experiences in the treatment of 24 patients with the nevoid basal-cell carcinoma syndrome. All the patients underwent surgical treatment, in 12 of them some of the tumours were treated with X-rays. Two patients were found to have 32 and 26 nevoid basal-cell carcinoma respectively.