In vitro and in vivo anti-Helicobacter pylori activity of selected medicinal plants employed for the management of gastrointestinal disorders.

Five medicinal plants Mentha piperita L., Trachyspermum ammi L., Viola odorata Linn.

Molecular Characterisation of Carbapenem-Resistant Enterobacteriaceae from Intensive Care Units.

Objective: To determine the molecular characterisation of carbapenem-resistant enterobacteriaceae (CRE) from patients admitted in intensive care units (ICUs) of a tertiary care hospital.

Study Design: Descriptive study.

Place And Duration Of Study: Department of Pathology and Microbiology, Pakistan Institute of Medical Sciences (PIMS), SZABMU, Islamabad, Pakistan, from July 2015 to March 2016.

Draft Genome Sequence of a - and -Harboring Pseudomonas aeruginosa Clinical Isolate from Pakistan.

We performed Illumina whole-genome sequencing on a carbapenem-resistant strain isolated from a cystic fibrosis patient with chronic airway colonization. The draft genome comprises 6,770,411 bp, including the carbapenemase and the extended-spectrum beta-lactamase This isolate harbors 3 prophages, 14 antibiotic resistance genes, and 257 virulence genes.

Incidence of metallo-beta-lactamase-producing Klebsiella pneumoniae isolates from hospital setting in Pakistan.

The aim of this study was monitoring and surveillance in different wards of the PIMS hospital, Islamabad, to understand emerging challenges of antibiotic resistance in particular association with most virulent serotypes of Klebsiella pneumoniae. The study was conducted during March 2015 to September 2015. The study showed that rate of isolation of K.

Prevalence and clinical burden of NDM-1 positive infections in pediatric and neonatal patients in Pakistan.

In a neonatal/pediatric Gram-negative infection study from Islamabad, 71/82 strains were carbapenem resistant with 12/82 positive for New Delhi Metallo-β-lactamase and many being extensively antibiotic resistant. Burden and outcome analysis on 9 patients showed that 4/9 died after inadequate therapy regardless of organism type.