TiO nanoparticle coatings on glass surfaces for the selective trapping of leukemia cells from peripheral blood.

Photodynamic therapy (PDT) using TiO nanoparticles has become an important alternative treatment for different types of cancer due to their high photocatalytic activity and high absorption of UV-A light. To potentiate this treatment, we have coated commercial glass plates with TiO nanoparticles prepared by the sol-gel method (TiO -m), which exhibit a remarkable selectivity for the irreversible trapping of cancer cells. The physicochemical properties of the deposited TiO -m nanoparticle coatings have been characterized by a number of complementary surface-analytical techniques and their interaction with leukemia and healthy blood cells were investigated.

Non-toxic doses of modified titanium dioxide nanoparticles (m-TiONPs) in albino CFW mice.

Modified titanium dioxide (m-TiONPs) is a novel photocatalytic nanomaterial. Its level of toxicity was evaluated to be used in photodynamic treatment for cervical cancer. In the toxicity studies (Irwin test, acute and repeated doses (10 days)), female albino Swiss Webster (CFW) mice, 28 days old were used; the m-TiONPs was administered in single 300, 600 and 5,000 mg/kg of body weight (b.

: A patent dataset report for research and development (R&D) analysis.

This work shows a patent database for that provides an overview of the patenting activity and trends in focused antiviral therapy with the use of triazole based compounds, glycoprotein, and protease inhibitors as possible treatment. The patent data was obtained from Orbit Intelligence Software using a patent family structure to get a big database that could be used for built patent landscape report (PLR), market analysis, technical and competitive intelligence, and monitoring and survey of a new ideas for the treatment of coronavirus diseases. The raw data is reported in four databases, which were classified according to different items: legal status (alive, dead), 1 application year (after 2015, 2011-2015, 2006-2010, 2001-2005), and Top 5 International Patents Classifications (IPC).

Synthesis and characterization of porous structures of rutile TiO /NaTiO/NaTiO for biomedical applications.

This method involves the use of molding, pressing and sintering techniques applied to different powder mixtures of TiO with sodium bicarbonate NaHCO (15 wt% and 30 wt% NaHCO), to obtain porous structures of rutile TiO/NaTiO/NaTiO and NaTiO/NaTiO for possible biomedical implant applications. The method validation includes X-ray diffraction patterns (XRD) analysis refined by the Rietveld method using X'Pert HighScore Plus. The surface morphology was observed by using a scanning electron microscopy (SEM) equipped with an energy dispersive spectrometer (EDS), and, finally, a Chinese hamster ovary (CHO) cell line was cultured with the porous structures to determine the effect of material composition on the cellular response using a LDH cytotoxicity assay.