"Prevalence and secular trend of neural tube defects in fetal deaths in Argentina, 1994-2019".

Background: Fetal deaths are a major source of information on the epidemiology of neural tube defects (NTDs; anencephaly and myelomeningocele). We analyzed NTDs prevalence and secular trend using fetal death records between 1994 and 2019 in Argentina.

Materials And Methods: Data were obtained from the Department of Statistics and Information of the Ministry of Health (DEIS).

Neonatal anthropometry of malformed newborns: A large South American population-based study.

Background: Population-based anthropometric evaluation of malformed newborns is scarce.

Objectives: To evaluate malformed newborns' foetal growth using the ICD 10 malformations' classification.

Methods: A study including 33,769 newborns (14,857 malformed and 18,912 nonmalformed), selected from 678,840 births from nine South American countries, period 2010-2018, was conducted.

[Secular trend in infant deaths by congenital malformations in Argentina (1980-2018)].

Introduction: Congenital malformations (CM) represent the second cause of infant death in Argentina.

Objective: To analyze the secular trend (1980-2018) of infant deaths due to CM at the regional and provincial level.

Material And Methods: The data come from the DEIS (Ministry of Health) and include the absolute number of deaths and live births and deaths by CM coded according to ICD-10 (Codes Q00-Q99).

Birth prevalence of congenital anomalies in Argentina, according to socioeconomic level.

Birth prevalence of congenital anomalies (CA) in Argentina is estimated around 1.7%. CA are the second leading cause of infant mortality.

Birth prevalence of congenital anomalies in the City of Buenos Aires, Argentina, according to socioeconomic level.

The goal of our study is to describe the prevalence of congenital anomalies (CA) in hospitals of the City of Buenos Aires, Argentina, according to two proxy variables of the socioeconomic level: health subsector, public (PUB) versus private/social security (PRI), and geographical location, northern (N) versus southern (S). The source of data was the National Network of Congenital Anomalies of Argentina (RENAC) (period 2010-2016). From a total of 228,208 births, 4872 newborns with CA were detected (2.

Microcephaly infant mortality in Brazil before zika outbreak.

Introduction: We present temporal and spatial variation of deaths from microcephaly in children under 1 year of age is analyzed at regional, state, and municipal level in the pre-Zika period in Brazil.

Materials And Methods: Data on births and deaths of infants with microcephaly was obtained from DATASUS from 1996 to 2013. Infant mortality rate from microcephaly (IMR-M) was estimated at Region, Federative Unit (UF), and Municipality level.

Infant mortality due to congenital malformations in the Autonomous City of Buenos Aires (1998-2015): Spatial, temporal analysis and relation to the socioeconomic status.

Introduction: In Argentina, congenital malformations (CM) account for the second cause of death among infants younger than 1 year.

Objective: To analyze spatial and temporal variation in infant mortality due to CM in the Autonomous City of Buenos Aires and its relation to a socioeconomic development indicator.

Materials And Methods: Births and deaths among infants younger than 1 year were coded using the International Classification of Diseases (ICD-10); data were provided by the Ministry of Health.

Epidemiology of sudden unexpected death in infancy in Argentina: secular trend and spatial variation.

Introduction: Infant mortality comprises deaths among infants younger than one year old. The proportion of sudden unexpected death in infancy (SUDI) varies by country and based on the cause of death.

Objective: To describe the spatial and temporal variation of SUDI in Argentina between 1991 and 2014 according to the International Classification of Diseases, tenth revision.

[Spatial and temporal analysis of infant mortality from microcephaly in Argentina (1998-2012)].

Due to the increase in cases of microcephaly caused by Zika virus in Brazil, the Ministry of Health of Argentina recommends increasing surveillance of this malformation. In order to deepen the knowledge of the epidemiological behavior of microcephaly in the country, infant mortality by microcephaly is analyzed between 1998 and 2012. The data come from the Direction of Statistics and Health Information (DEIS).

Relationship between infant mortality and altitude in the Northwest region of Argentina.

Introduction: Given its location on the Andes, the Northwest region of Argentina is geographically, socioeconomically, culturally, and biologically heterogeneous, and this is reflected on an infant mortality rate (IMR) that is higher than in any other Argentine region.

Objetive: To estimate IMR, neonatal mortality rate (NMR), and post-neonatal mortality rate (PNMR), and to analyze their spatial and temporal variations using secular trends and the relative risk based on altitudinal zones.

Population And Method: This was a retrospective, descriptive, correlational study based on birth and death data recorded in the Northwest region of Argentina (1998-2010); IMR, NMR, PNMR, secular trends, and the relative risk of death were calculated by district and altitudinal zone (districts at < 2000 meters above sea level, lowlands; at > 2000 meters above sea level, highlands) by means of a cluster analysis.

[Infant mortality from congenital malformations in Chile: temporal and spatial analysis, 1997-2011].

Objective: To analyze the spatial and temporal distribution (1997-2011) of infant mortality resulting from congenital malformations (CM) in Chile.

Methods: Data on births and deaths among infants aged less than one year using ICD-10 coding were obtained from the National Statistics Institute. The percentage of deaths from CM (PD-CM) and the infant mortality rate from CM (IMR-CM) during three different periods (1997-2001, 2002-2009, 2007-2011) were estimated for Chile's administrative and natural regions (Norte Grande, Norte Chico, Central, Austral, and Sur), broken down by systems (nervous, cardiovascular, digestive, genitourinary, musculoskeletal, and chromosomal abnormalities) and by 28 specific malformations.

Biosocial correlates and spatial distribution of consanguinity in South America.

Objective: To analyze potential biosocial factors in consanguineous unions according to the level of consanguinity and its spatial distribution in South America.

Methods: The data used came from the Latin American Collaborative Study of Congenital Malformations. Information on 126,213 nonmalformed newborns out of 6,014,749 births was used.

Random inbreeding, isonymy, and population isolates in Argentina.

Population isolates are an important tool in identifying and mapping genes of Mendelian diseases and complex traits. The geographical identification of isolates represents a priority from a genetic and health care standpoint. The purpose of this study is to analyze the spatial distribution of consanguinity by random isonymy (F ST) in Argentina and its relationship with the isolates previously identified in the country.

[Infant mortality due to congenital malformations and socioeconomic status: the case of Argentina].

Objective: Compare the infant mortality rate due to congenital malformations ( IMRCM) and the percentage of deaths due to congenital malformations (%DCM) with sociodemographic and economic characteristics in Argentina.

Methods: The Argentine study population resided in 511 departments of 23 provinces, grouped into five geographic regions (Northwest, Northeast, Central, Cuyo, and Patagonia). The analyzed variables were the IMRCM and the %DCM calculated on the basis of births and deaths during 2002-2006 period.

[Anencephaly related infant mortality in Argentina: spatial and temporal analysis (1998-2007)].

Objective: Analyze the spatial and temporal distribution of infant mortality by anencephaly in Argentina in relation with folic acid fortification phases.

Population And Methods: Data came from certificates of live births and deaths in children under 1 year, for the 1998-2007 period (Argentine Ministry of Health). The infant mortality rate attributable to anencephaly for Argentina, geographical regions, provinces and departments were estimated according to the different phases of mandatory fortification with folic acid.

[Prevalence of malnutrition in institutionalized intellectually disabled patients].

As patients with intellectual and developmental disability (ID) may be more exposed to unfavorable factors, they are at higher risk of suffering nutritional alterations. Our objective was to determine prevalence of malnutrition in institutionalized patients with ID. An evaluation of the nutritional status through determination of transversal anthropometric parameters of weight (kg) and height (cm) was made on 614 individuals (352 men and 262 women) institutionalized at Colonia Nacional Montes de Oca, Buenos Aires Province, Argentina.

Isonymy structure of Buenos Aires city.

The isonymy structure of Buenos Aires was studied based on its surname frequency. Information on 2,552,359 voters of the 28 Buenos Aires districts was used to estimate Lasker's coefficient of relationship by isonymy (R(i)), surname diversity according to Fisher's alpha, the coefficient of consanguinity resulting from random isonymy (F), and Nei's, Lasker's and the Euclidean isonymy distances. These distances were correlated with geographic distances, which were calculated by assigning an arbitrary point to each district and measuring distances on a map of the city.

[Analysis of infant mortality from congenital malformations in Argentina during the 2002-2006 period].

Objective: To analyze the trend and spatial distribution of infant mortality from congenital malformations in Argentina between 2002 and 2006.

Materials And Methods: Data were provided by the Ministry of Public Health. Congenital malformations were classified according to the International Classification of Diseases, 10th revision.

[Smith-Magenis syndrome: case report and review].

Smith-Magenis syndrome (SMS) is characterized by distinctive facial features that progress with age, developmental delay, cognitive impairment, and behavioral abnormalities associated with molecular anomaly in 17p11.2. Treatment includes: early childhood intervention programs, special education, vocational training later in life, and speech/language, physical, and occupational, behavioral, and sensory integration therapies.

Acitretin embryopathy: a case report.

Background: Acitretin is an aromatic retinoid analog of vitamin A. Drugs of this group are well-known teratogenic agents. Nevertheless, acitretin embryopathy has been described only in fetuses.