LGBTQ+ family building: progress but lots more to do.

Great strides have been made in society and in reproductive endocrinology and infertility in support of lesbian, gay, bisexual, transgender, and queer/questioning. Although many of the concepts used in heterosexual reproduction can be applied to the lesbian, gay, bisexual, transgender, and queer/questioning plus community, there are specific differences that should be understood to provide the highest level of care to this community.

Climate change and human health: a primer on what women's health physicians can do on behalf of their patients and communities.

Purpose Of Review: To describe the current state of knowledge on the impact on climate change on women's health and to highlight opportunities for healthcare providers to serve as advocates and subject matter experts.

Recent Findings: Healthcare providers are a uniquely respected voice in society but have not used this advantage to advocate for their communities and participate in mitigation, adaptation, and resiliency efforts on behalf of their patients and communities.

Summary: Healthcare providers feel that climate change is real, is human caused, and is currently or will shortly negatively impact their patients.

Concordance of hemoglobin A1c and reproductive hormone levels in menstrual and venous blood.

Objective: To explore whether menstrual blood collected via a modified menstrual pad is a surrogate for venous blood drawn in analyzing hemoglobin A1c (HbA1c) and fertility-associated hormones.

Design: Cross-sectional study.

Setting: Clinical testing laboratory.

Utility of Repeat Uterine Cavity Evaluation in the Infertility Workup.

Uterine cavity abnormalities contribute to infertility. The purpose of this study was to evaluate the incidence, recurrence rates, and risk factors for uterine cavity abnormalities in women undergoing infertility workup and treatment, focusing on the utility of routinely repeated imaging. Retrospective cohort study at single academic medical center of 833 infertile women who had uterine cavity evaluations performed at least 9 months apart.

Meeting the demand for fertility services: the present and future of reproductive endocrinology and infertility in the United States.

The field of reproductive endocrinology and infertility (REI) is at a crossroads; there is a mismatch between demand for reproductive endocrinology, infertility and assisted reproductive technology (ART) services, and availability of care. This document's focus is to provide data justifying the critical need for increased provision of fertility services in the United States now and into the future, offer approaches to rectify the developing physician shortage problem, and suggest a framework for the discussion on how to meet that increase in demand. The Society of REI recommend the following: 1.

The no-man's land of nontubal ectopic and cesarean section scar pregnancies.

Nontubal ectopic pregnancy (NTEP) and cesarean section scar pregnancy (CCSP) are a relatively uncommon but potentially very dangerous conception event. If diagnosed early, they can be treated very effectively. Cesarean section scar ectopic is unique in that expectant management may allow them to persist longer, but with overwhelmingly catastrophic consequences.

Reproductive endocrinologist and infertility specialists' knowledge, skills, behaviors, and attitudes regarding the care for transgender and gender-diverse individuals.

Objective: To investigate associations between reproductive endocrinology and infertility (REI) providers' prior training and current knowledge, skills, attitudes, and behaviors regarding fertility preservation and family building for transgender and gender-diverse (T/GD) patients.

Design: The survey was distributed to members of the Society for Reproductive Endocrinology and Infertility, the REI-physician-focused professional body within the American Society for Reproductive Medicine, with additional participants recruited through snowball sampling.

Results: Participants (n = 206) reported on training in T/GD care; 51% endorsed prior training.

Oocyte and embryo cryopreservation in assisted reproductive technology: past achievements and current challenges.

Cryopreservation has revolutionized the treatment of infertility and fertility preservation. This review summarizes the milestones that paved the way to the current routinary clinical implementation of this game-changing practice in assisted reproductive technology. Still, evidence to support "the best practice" in cryopreservation is controversial and several protocol adaptations exist that were described and compared here, such as cumulus-intact vs.

Cost-effectiveness of IVF with PGT-M/A to prevent transmission of spinal muscular atrophy in offspring of carrier couples.

Purpose: To evaluate the cost-effectiveness of in-vitro fertilization with preimplantation genetic testing for aneuploidy and monogenic disorders (IVF with PGT-M/A) to prevent transmission of spinal muscular atrophy to offspring of carrier couples.

Methods: A decision-analytic model was created to compare the cost-effectiveness of IVF with PGT-M/A to unassisted conception with prenatal diagnostic testing and termination (if applicable). IVF with PGT-M/A costs were determined using a separate Markov state-transition model.

Implementation of a comprehensive fertility biobanking initiative.

Objective: To present the framework of Stanford Fertility and Reproductive Health's comprehensive reproductive biobanking initiatives and the results of the first year of recruitment.

Design: Technical description article.

Setting: Academic fertility center.

The third degree: climate change and reproductive health.

Climate change is a public health emergency, yet the medical community has been inconsistent in its understanding and engagement of the crisis. Reproductive endocrinology and infertility and reproductive biology will be impacted broadly by the changing climate. This Views and Reviews hopes to enlist reproductive endocrinology and infertility specialists to first understand the issues and then take action to support mitigation and accommodation efforts.

Is living in a region with high groundwater arsenic contamination associated with adverse reproductive health outcomes? An analysis using nationally representative data from India.

Background: Exposure to groundwater arsenic via drinking water is common in certain geographies, such as parts of India, and causes a range of negative health effects, potentially including adverse reproductive health outcomes.

Methods: We conducted an ecological analysis of self-reported rates of stillbirth, recurrent pregnancy loss, and infertility in relation to groundwater arsenic levels in India. We used a gridded, modeled dataset of the probability of groundwater arsenic exceeding 10 μg/L (World Health Organization drinking water limit) to calculate mean probabilities at the district level (n = 599 districts).