Evaluation of phyto-gallic acid as a potential inhibitor of efflux pump mediated tetracycline resistance: an and in-silico study.

Plants contain many bioactive compounds with potent antibacterial and efflux pump inhibitory activity (EPI). In this study, gallic acid extracted from pomegranate molasses by analytical HPLC holds promise as an EPI drug for mediated tetracycline resistance, it lowered the bacterial resistance and reversed the mechanism family efflux pump, using molecular technique and molecular docking analysis. Extracted gallic acid combined with tetracycline demonstrated a significant decrease in the minimal inhibitory concentration MIC compared to its single activity.

CE-DAD Determination of Scutellarein and Caffeic Acid in Abelia triflora Crude Extract.

A precise, accurate, selective and sensitive capillary electrophoresis method using a diode array detector was developed for the first time for the determination of both scutellarein (SLN) and caffeic acid (CAA) in prepared Abelia triflora extract. Electrophoretic analysis was performed using a background electrolyte solution consisting of borax buffer (40 mM, pH 9.2) and a 200-nm detection wavelength.