Publications by authors named "Ru-ying Hu"

Objective: This study aimed to quantify the severity of metabolic syndrome(MetS) and investigate its association with cardiovascular disease(CVD) risk on Chinese adults.

Methods: 13,500 participants from the Zhejiang Adult Chronic Disease Study were followed up between 2010 and 2021. A continuous MetS severity score derived from the five components of MetS was used to quantify MetS severity, and the association between MetS severity and the risk of incident CVD was assessed using Cox proportional hazard and restricted cubic spline regression.

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  • The study aimed to assess how whole fresh fruit intake affects the risk of developing type 2 diabetes (T2D) in individuals with varying glucose regulation, focusing on a large group of non-diabetic participants aged 40 and older in China.
  • Over a follow-up period of 3.8 years, researchers found a significant inverse relationship between fruit consumption and diabetes risk; specifically, each additional 100 grams of fruit consumed daily corresponded to a 2.8% reduction in diabetes risk.
  • Results indicated that this protective effect was most pronounced in individuals with normal glucose tolerance, while no significant association was observed in those with prediabetes.
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Objective: The relationship between serum uric acid (SUA) levels and glycemic indices, including plasma glucose (FPG), 2-hour postload glucose (2h-PG), and glycated hemoglobin (HbA1c), remains inconclusive. We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.

Methods: The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.

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  • A study conducted in Zhejiang Province, China, explored the link between diabetes and thyroid cancer risk, involving 2,937 thyroid cancer cases matched with 2,937 healthy controls from 2015 to 2017.
  • The study found that overall, there was no significant association between diabetes or its duration and thyroid cancer risk.
  • However, in certain groups (older adults, females, overweight/obese individuals, and those with a family history of diabetes), shorter diabetes duration (≤ 5 years) was linked to a lower risk of developing thyroid cancer.
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Objective: To investigate the sleep duration and correlates from lifestyle, dietary and weight control behaviors in Chinese adolescents.

Methods: Data were from 2017 Zhejiang Youth Risk Behavior Survey. A total of 17059 adolescents were included in this study and sleep duration and other behaviors information was collected via a self-reported questionnaire.

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Background: Limited population-based studies have investigated the secular trend of prevalence of gestational diabetes mellitus (GDM) in mainland China. Therefore, this study aimed to estimate the prevalence of GDM and time trends in Chinese female population.

Methods: Based on Diabetes Surveillance System of Zhejiang Province, 97,063 diagnosed GDM cases aged 20-50 years were identified from January 1, 2016 to December 31, 2018.

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  • - The study investigated the relationship between reproductive factors, such as menstrual history and breastfeeding, and thyroid cancer risk in Chinese women, finding inconsistent results in prior research.
  • - Data was collected through a matched case-control study involving 2,261 pairs of female subjects, with analysis done using logistic regression to determine odds ratios for thyroid cancer risk.
  • - The results indicated that a later age at first pregnancy and longer breastfeeding duration were linked to a reduced risk of thyroid cancer, particularly in women aged 50 or younger.
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Introduction: Previous research has indicated that weight control behaviors are linked to cigarette smoking, whether these relationships extend to electronic cigarettes (e-cigarettes) is unknown. This study aims to examine the association between weight control behaviors and current e-cigarette usage among middle and high school students in China.

Methods: Based on the 2017 Zhejiang Youth Risk Behavior Survey, 17359 students were included and relevant data involving e-cigarette and weight control behaviors were collected via self-reported questionnaires.

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Aims: Population-based incidence data are paramount to assess the effects of prevention strategies for diabetes, yet the relevant studies in mainland China are scarce. This study is aimed at estimating the type 2 diabetes mellitus (T2DM) incidence and time trends in Chinese adults. .

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Objectives: The present study aims at examining the prevalence of awareness and current use of electronic cigarettes (e-cigarettes) among middle and high school students from Zhejiang, China. Smoking-related factors associated with e-cigarettes use will also be explored.

Methods: This cross-sectional study was based on 2017 Zhejiang Youth Risk Behavior Survey.

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Background: Few accurate up-to-date studies provide liver cancer mortality and survival information in Zhejiang province. This research aimed to depict the mortality and survival of liver cancer in Zhejiang province in China during 2005-2010.

Methods: The data were collected from the Zhejiang Chronic Disease Surveillance Information and Management System, and the mortality rates of liver cancer were calculated by gender, age, and areas.

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Background: Although exercise seems to be beneficial for type 2 diabetes mellitus (T2DM) patients, there is limited research elucidating the optimal accessible indices of adiposity and insulin resistance for identifying elderly T2DM patients with poor glycemic control, which could be improved by performing regular exercise.

Methods: A community-based, cross-sectional study was conducted with 918 Chinese elderly individuals with T2DM in Zhejiang. Relevant risk factors for poor glycemic control, as determined using glycated haemoglobin A1c (HbA1c) > 7%, were explored using logistic regression analyses and included body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR), fasting blood glucose (FBG), triglycerides (TGs), total cholesterol (TC), the product of fasting triglycerides and glucose (TyG), visceral adiposity index (VAI), lipid accumulation product (LAP), TyG-BMI, and TyG-WC.

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Aims/introduction: Evidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes in Chinese adults.

Materials And Methods: The cross-sectional data were from the China Kadoorie Biobank study, which enrolled approximately 500,000 adults aged 30-79 years from 10 diverse regions of China.

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Several studies have been carried out to examine the association between cigarette smoking during pregnancy and risk of developing gestational diabetes mellitus (GDM), yet the findings are mixed. Therefore, we aimed to estimate the relationship between cigarette smoking during pregnancy and GDM risk. PubMed, ScienceDirect, and Cochrane Library databases were searched up to December 2017.

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  • - The study aimed to identify factors affecting the age at natural menopause among over 17,000 postmenopausal Chinese women as part of the China Kadoorie Biobank research.
  • - It found the average age at onset of natural menopause was around 48.94 years, with specific lifestyle and demographic factors influencing whether menopause occurred early or late.
  • - Key associations included that higher education, moderate meat consumption, and having more children generally led to later menopause, while smoking, being underweight, and a high activity level were linked to earlier menopause.
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Introduction: Evidence suggests that smoking by family members and friends is a strong predictor of smoking uptake in adolescents, yet the influence on electronic cigarette (e-cigarette) use has not been systematically reviewed and quantified.

Methods: Relevant studies were identified by searches of the PubMed and ScienceDirect databases up to December 2016. The summary odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model.

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  • * Researchers analyzed data from over 17,000 women and found that 7.54% had type 2 diabetes.
  • * Results indicated that women who experienced menopause later (≥53 years) were 1.21 times more likely to have diabetes compared to those who underwent menopause between 46-52 years.
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Background: The associations of occupational activity (OA), commuting, leisure-time physical activity (LTPA), and sitting with overweight/obesity in working adults are controversial. This study explored these factors with the risk of overall and abdominal overweight/obesity in a Chinese working population and whether these associations differ by gender.

Methods: A cross-sectional study was conducted.

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Background: Life expectancy is a statistical measure of the average time an organism is expected to live. The purpose of this study was to evaluate the impact of injury-related mortality on life expectancy in Zhejiang Province.

Methods: Our study used standard life tables to calculate life expectancy and cause-removed life expectancy based on mortality data from the Zhejiang Chronic Disease Surveillance System.

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  • The study aimed to assess the links between sleep duration, snoring, and diabetes among different gender and menopausal status groups in rural China.
  • Researchers analyzed data from over 57,000 participants aged 30-79 using logistic regression to determine the odds of diabetes based on sleep patterns and snoring.
  • Results indicated a U-shaped relationship between sleep duration and diabetes risk in postmenopausal women, while snoring was associated with diabetes across all groups, impacted by factors like socioeconomic status and health behaviors.*
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The microRNA-21 (miR-21) is known to play a major role in cancer progression; however, its function in the cardiovascular system appears to be even more complex and conflicting. To characterize miR-21 expression in the plasma of individuals with or without metabolic syndrome (MetS), 58 MetS cases and 96 non-MetS controls were investigated. Expression levels of miR-21 were significantly decreased in the circulation of MetS subjects (OR=0.

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Increasing evidence indicates that cigarette smoking is a strong predictor of electronic cigarettes (e-cigarettes) use, particularly in adolescents, yet the effects has not be systematically reviewed and quantified. Relevant studies were retrieved by searching three databases up to June 2015. The meta-analysis results were presented as pooled odds ratios (ORs) with 95% confidence intervals (CIs) calculated by a random-effects model.

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Evidence indicates an increased cancer risk among type 2 diabetes mellitus (T2DM) patients, yet studies in mainland China are scarce. Based on Diabetes Surveillance System linking to Cancer Surveillance System of Zhejiang Province in China, we explored the cancer risk among T2DM patients. Totally, 327,268 T2DM patients were identified and followed from January 1, 2007 to December 31, 2013.

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Aims/introduction: Many studies have been carried out to examine the association between sugar-sweetened beverages and the incident of type 2 diabetes, but results are mixed. The aim of the present study was to estimate the association between sugar-sweetened beverage intake and the risk of type 2 diabetes.

Materials And Methods: PubMed, Springer Link and Elsevier databases were searched up to July 2014.

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Background: Whether cigarette smoking and alcohol consumption are associated with the risk of metabolic syndrome (MetS) remains controversial. This study investigated the associations of cigarette smoking and alcohol consumption with MetS in a male population in China.

Methods: We conducted a cross-sectional study.

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