Publications by authors named "Ru-Qi Wang"
Nat Prod Res
October 2024
Article Synopsis
- Ingenane-type diterpenoids (ITDs) from a specific plant genus exhibit strong anti-cancer effects on non-small cell lung cancer (NSCLC) cells, although their precise molecular mechanism remains unclear.
- Network pharmacology analysis identified key interactions between proteins SRC and PI3K, highlighting their role in the PI3K/Akt signaling pathway.
- The compound 13-oxyingenol-dodecanoate (13OD) was validated as an effective anti-cancer agent, as it inhibited NSCLC cell growth by inducing apoptosis and down-regulating the SRC/PI3K/Akt pathway.
