Efficacy study of intermittent theta burst stimulation(iTBS) in the treatment of adolescents with affective disorders.

Background: Affective disorders are the leading cause of disability worldwide. Intermittent theta burst stimulation (iTBS) is a safe and effective brain stimulation therapy for reducing depressive symptoms in adolescents. The purpose of this study is to investigate the clinical efficacy of iTBS in treating adolescent patients with depressive disorders and the factors influencing clinical symptoms.

Suppression and Revival of Superconducting Phase Coherence in Monolayer FeSe/SrTiO.

Monolayer FeSe grown on SrTiO (FeSe/STO) is an interfacial high-temperature superconductor distinctively different from bulk FeSe. However, the superconducting phase coherence of the interface is challenging to probe due to its fragility in the atmosphere. Here, we perform mutual inductance under ultrahigh vacuum on FeSe/STO in combination with band mapping by angle-resolved photoemission spectroscopy.

Spatially homogeneous few-cycle compression of Yb lasers via all-solid-state free-space soliton management.

The high power and variable repetition-rate of Yb femtosecond lasers makes them very attractive for ultrafast science. However, for capturing sub-200 fs dynamics, efficient, high-fidelity and high-stability pulse compression techniques are essential. Spectral broadening using an all-solid-state free-space geometry is particularly attractive, as it is simple, robust and low-cost.

High temperature superconductivity at FeSe/LaFeO interface.

Enormous enhancement of superconducting pairing temperature (T) to 65 K in FeSe/SrTiO has made it a spotlight. Despite the effort of interfacial engineering, FeSe interfaced with TiO remains the unique case in hosting high T, hindering a decisive understanding on the general mechanism and ways to further improving T. Here we constructed a new high-T interface, single-layer FeSe interfaced with FeO-terminated LaFeO.

Oxygen Adsorption Induced Superconductivity in Ultrathin FeTe Film on SrTiO(001).

The phenomenon of oxygen incorporation-induced superconductivity in iron telluride (FeTe, with antiferromagnetic (AFM) orders) is intriguing and quite different from the case of FeSe. Until now, the microscopic origin of the induced superconductivity and the role of oxygen are far from clear. Here, by combining in situ scanning tunneling microscopy/spectroscopy (STM/STS) and X-ray photoemission spectroscopy (XPS) on oxygenated FeTe, we found physically adsorbed O molecules crystallized into (2/3 × 2) structure as an oxygen overlayer at low temperature, which was vital for superconductivity.

[Seasonal dynamics of soil microbial community and enzyme activities in Hippophae rhamnoides plantation].

We investigated the effects of forest age and season on soil microbial community structure and enzyme activities in Hippophae rhamnoides plantation. The results showed that the amounts of total PLFAs, bacterial PLFAs, and fungal PLFAs increased with the increases of forest age. The highest values presented in mature plantation (CL).

[Baicalein enhances the gap junction in the TM4 Sertoli cells of mice].

Objective: To investigate the effect of baicalein on the gap junction intercellular communication (GJIC) in the TM4 Sertoli cells of the mouse testis and its related mechanism.

Methods: We measured the cytotoxicity of different concentrations of baicalein on the TM4 Sertoli cells in the mouse testis by MTT, detected the fluorescence transfer of the TM4 Sertoli cells by parachute assay, and determined the expression of the protein connexin 43 ( Cx43) in the baicalein-treated cells by Western blot and immunofluorescence assay.

Results: Baicalein produced no obvious cytotoxicity on the TM4 Sertoli cells at the concentration below 60 µmol/L but significantly increased their GJIC at 0-20 µmol/L (P < 0.

Reprogramming of active and repressive histone modifications following nuclear transfer with rabbit mesenchymal stem cells and adult fibroblasts.

Following nuclear transfer (NT) the epigenetic state of a donor nucleus must be reprogrammed to an embryonic one. To evaluate the efficiency of nuclear reprogramming, we monitored the levels of histone H3 di/tri-methylated on lysine 4 (H3K4m2/3), a marker for transcriptionally active/permissive euchromatin, and of histone H3 tri-methylated on lysine 27 (H3K27m3), a modification associated with facultative heterochromatin, in embryos cloned using rabbit mesenchymal stem cells (MSC) and adult fibroblasts (RAF) isolated from the same animals. In vivo fertilized, in vitro cultured embryos served as controls.

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes.

Background: In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA demethylation in the zygote has been documented for several mammalian species, including mouse, rat, pig, human and cow, but questioned to occur in rabbit.

Rabbit somatic cell cloning: effects of donor cell type, histone acetylation status and chimeric embryo complementation.

The epigenetic status of a donor nucleus has an important effect on the developmental potential of embryos produced by somatic cell nuclear transfer (SCNT). In this study, we transferred cultured rabbit cumulus cells (RCC) and fetal fibroblasts (RFF) from genetically marked rabbits (Alicia/Basilea) into metaphase II oocytes and analyzed the levels of histone H3-lysine 9-lysine 14 acetylation (acH3K9/14) in donor cells and cloned embryos. We also assessed the correlation between the histone acetylation status of donor cells and cloned embryos and their developmental potential.