Introduction: Organ donation can be a life-saving opportunity for patients with severe organ failure. In India, the rate of organ donation of the deceased Indian population is exceptionally low. This necessitates enhancing awareness regarding organ donation among health care professionals and students, which can motivate the general population.
View Article and Find Full Text PDFJ Young Pharm
October 2010
Drug-drug interaction between esomeprazole at therapeutic and higher doses and sulfonylureas was studied. Sulfonylureas (tolbutamide 40 mg/kg and glibenclamide 40 µg/kg) were administered and the time to onset of hypoglycemia, the duration of the hypoglycemia, and the peak hypoglycemia were determined. Esomeprazole (1.
View Article and Find Full Text PDFThe antiulcer and in vitro anti-inflammatory activities of the aerial parts of Enicostemma littorale against aspirin, ethanol, and pyloric ligation-induced ulcers in rats and bovine serum albumin denaturation were studied. The extract (200 mg/kg and 400 mg/kg po) was administered to the overnight fasted rats, one hour prior to aspirin / alcohol / pyloric ligation challenge. The ulcer index, tissue GSH levels, and lipid peroxidation levels were estimated in all the models of ulcers and the volume of gastric secretion, acidity, and pH, were estimated in the pyloric ligation model of ulcers.
View Article and Find Full Text PDFThe 70% ethanolic extract of Peltophorum pterocarpum leaves were investigated for its hepatoprotective effect against paracetamol induced acute liver damage on albino wister rats. Paracetamol (2gm/kg, po) significantly elevated the serum levels of biochemical markers like SGPT, SGOT, ALP, bilirubin (total and direct), total cholesterol, triglycerides and depleted tissue GSH and increased the lipid peroxidation. upon administration of paracetamol (2mg/kg p.
View Article and Find Full Text PDFA three-month prospective study of the 1026 pensioners attending the Accident and Emergency Department (A.E.D.
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