Achieving clinical remission in asthma with mepolizumab: a subanalysis on vitamin D as a predictor of response.

Objective: Mepolizumab, an anti-IL-5 monoclonal antibody, has shown promise in reducing exacerbations and steroid dependency in severe eosinophilic asthma. This study aims to evaluate the effectiveness of mepolizumab in achieving clinical remission in asthma over 12 months and explore Vitamin D levels as a predictor of response.

Method: We assessed Asthma Control Questionnaire (ACQ) scores, spirometry, number of exacerbations, oral corticosteroid (OCS) use, and inhaled corticosteroid (ICS) use in 32 patients, observing significant clinical improvements.

Stochastic gradient descent algorithm for the predictive modelling of grate combustion and boiler dynamics.

Pressure and water level control are quite challenging in grate-fired boilers due to higher combustion lag. Fluctuation in the pressure and the water level is more evident in the coal-fired grate boilers due to the presence of lower volatile and higher char. This results in suboptimal operation and poor performance of the boiler.

Pilomatricoma mimicking small round cell tumor on fine needle aspiration cytology: a case report.

Background: Pilomatricoma, a benign skin adnexal tumor, frequently leads to false positive diagnosis cytologically. We report a rapidly growing nodular swelling misdiagnosed as round cell tumor cytologically and found to be pilomatricoma histopathologically.

Case: A 32-year-old man presented with a rapidly growing, mobile nodule on his left arm for 4 months with fixed, shiny overlying skin.

Monoclonal antibodies for the histopathological diagnosis of cervical neoplasia.

Five monoclonal antibodies (Ca1, HMFG 1 and 2, 8.30.3 and 77.