In the context of automatic medical image segmentation based on statistical learning, raters' variability of ground truth segmentations in training datasets is a widely recognized issue. Indeed, the reference information is provided by experts but bias due to their knowledge may affect the quality of the ground truth data, thus hindering creation of robust and reliable datasets employed in segmentation, classification or detection tasks. In such a framework, automatic medical image segmentation would significantly benefit from utilizing some form of presegmentation during training data preparation process, which could lower the impact of experts' knowledge and reduce time-consuming labeling efforts.
View Article and Find Full Text PDFObjectives: This study combined two novel approaches in oncology patient outcome predictions-body composition and radiomic features analysis. The aim of this study was to validate whether automatically extracted muscle and adipose tissue radiomic features could be used as a predictor of survival in patients with non-small cell lung cancer.
Methods: The study included 178 patients with non-small cell lung cancer receiving concurrent platinum-based chemoradiotherapy.
Objectives: We developed a method for a fully automated deep-learning segmentation of tissues to investigate if 3D body composition measurements are significant for survival of Head and Neck Squamous Cell Carcinoma (HNSCC) patients.
Methods: 3D segmentation of tissues including spine, spine muscles, abdominal muscles, subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), and internal organs within volumetric region limited by L1 and L5 levels was accomplished using deep convolutional segmentation architecture - U-net implemented in a nnUnet framework. It was trained on separate dataset of 560 single-channel CT slices and used for 3D segmentation of pre-radiotherapy (Pre-RT) and post-radiotherapy (Post-RT) whole body PET/CT or abdominal CT scans of 215 HNSCC patients.
IEEE Trans Med Imaging
November 2022
In recent years, there were many suggestions regarding modifications of the well-known U-Net architecture in order to improve its performance. The central motivation of this work is to provide a fair comparison of U-Net and its five extensions using identical conditions to disentangle the influence of model architecture, model training, and parameter settings on the performance of a trained model. For this purpose each of these six segmentation architectures is trained on the same nine data sets.
View Article and Find Full Text PDFSarcopenia is a muscle disease which previously was associated only with aging, but in recent days it has been gaining more attention for its predictive value in a vast range of conditions and its potential link with overall health. Up to this point, evaluating sarcopenia with imaging methods has been time-consuming and dependent on the skills of the physician. The solution for this problem may be found in artificial intelligence, which may assist radiologists in repetitive tasks such as muscle segmentation and body-composition analysis.
View Article and Find Full Text PDFHelicobacter pylori (H. pylori) plays an important role in the pathogenesis of the upper gastrointestinal tract diseases in both children and adults. The aim of this paper was to assess the differences between the clinical course of the disease in children and adults.
View Article and Find Full Text PDFZentralbl Allg Pathol
November 1975
A case report on an anencephalus with numerous heterotopias of brain tissue in the lungs is presented. The presumable period of development and other embryological aspect of this exceptional malformation are discussed.
View Article and Find Full Text PDFVerh Dtsch Ges Pathol
April 1974
Ann Univ Mariae Curie Sklodowska Med
August 1971