Renal function is related to severity of coronary artery calcification in elderly persons: the Rotterdam study.

Background: Coronary artery calcification (CAC) has been proposed to be the underlying mechanism of the increased risk of coronary heart disease with reductions in glomerular filtration rate (GFR). Since renal function diminishes with aging we examined the association between GFR and CAC in the Rotterdam Study, a population-based study of elderly individuals.

Methods: The study was performed in 1703 subjects without a history of coronary heart disease.

Coronary calcium score improves classification of coronary heart disease risk in the elderly: the Rotterdam study.

Objectives: The purpose of this study was to examine the effect of coronary artery calcium (CAC) on the classification of 10-year hard coronary heart disease (CHD) risk and to empirically derive cut-off values of the calcium score for a general population of elderly patients.

Background: Although CAC scoring has been found to improve CHD risk prediction, there are limited data on its impact in clinical practice.

Methods: The study comprised 2,028 asymptomatic participants (age 69.

Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study.

Background: Epidemiologic and experimental data suggest a cardioprotective effect of n-3 (omega-3) fatty acids from fish [eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA)].

Objective: The objective was to examine the association of fish and EPA plus DHA intakes with coronary calcification in a general older population.

Design: Diet was assessed between 1990 and 1993 by using a semiquantitative 170-item food-frequency questionnaire.

Volumetric measurement of pulmonary nodules at low-dose chest CT: effect of reconstruction setting on measurement variability.

Objective: To assess volumetric measurement variability in pulmonary nodules detected at low-dose chest CT with three reconstruction settings.

Methods: The volume of 200 solid pulmonary nodules was measured three times using commercially available semi-automated software of low-dose chest CT data-sets reconstructed with 1 mm section thickness and a soft kernel (A), 2 mm and a soft kernel (B), and 2 mm and a sharp kernel (C), respectively. Repeatability coefficients of the three measurements within each setting were calculated by the Bland and Altman method.

Coronary calcium mass scores measured by identical 64-slice MDCT scanners are comparable: a cardiac phantom study.

To assess whether absolute mass scores are comparable or differ between identical 64-slice MDCT scanners of the same manufacturer and to compare absolute mass scores to the physical mass and between scan modes using a calcified phantom. A non-moving anthropomorphic phantom with nine calcifications of three sizes and three densities was scanned 30 times on three 64-slice MDCT scanners of manufacturer A and on three 64-slice MDCT scanners of manufacturer B in both sequential and spiral scan mode. The mean mass scores and mass score variabilities of seven calcifications were determined for all scanners; two non-detectable calcifications were omitted.