Publications by authors named "Roza V Menshova"
Laminaran and three fractions of fucoidan were isolated from brown alga Alaria angusta. The laminaran AaL was characterized as a typical 1,3;1,6-β-D-glucan (ratio of bonds 1,3:1,6 = 10:1). Fucoidans AaF1 and AaF2 are sulfated heteropolysaccharides, containing fucose, galactose, mannose and xylose.
View Article and Find Full Text PDFA sulfated galactofucan SgF (MW 123kDa) was purified from the brown alga Saccharina gurjanovae. Polysaccharide was depolymerized by autohydrolysis at 25 and 60°C, and products were studied by mass spectrometry and (13)C NMR spectroscopy. According to results of investigation, the main chain of this polysaccharide is built of a repeating units →3)-α-L-Fucp-(2,4-OSO3(-))-(1→.
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- The high molecular weight laminaran from the brown alga Eisenia bicyclis was analyzed using various methods, revealing it as a 1,3;1,6-β-D-glucan with a greater presence of 1,6-linked glucose residues.
- The structure shows that the 1,3-linked glucose blocks mainly consist of disaccharide fragments, while the 1,6-linked residues are primarily located at the non-reduced ends of the molecules, affecting their polymerization degree.
- Both laminaran and its enzymatic hydrolysis products exhibited inhibition of human melanoma and colon cancer cell growth, suggesting their potential as antitumor agents when modified for specific molecular weights.
Three different fucoidan fractions were isolated and purified from the brown alga, Sargassum mcclurei. The SmF1 and SmF2 fucoidans are sulfated heteropolysaccharides that contain fucose, galactose, mannose, xylose and glucose. The SmF3 fucoidan is highly sulfated (35%) galactofucan, and the main chain of the polysaccharide contains a →3)-α-L-Fucp(2,4SO₃⁻)-(1→3)-α-L-Fucp(2,4SO₃⁻)-(1→ motif with 1,4-linked 3-sulfated α-L-Fucp inserts and 6-linked galactose on reducing end.
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