Decreased red blood cells deformability in acute pancreatitis in the rat. Effect of tirilazad mesylate.

Unlabelled: The ability of erythrocytes to deform is the key feature in maintain the microcirculation. Both acute pancreatitis and decrease in deformability of erythrocytes are associated with increase in lipid peroxidation as a result of excess production of free radicals. Hence the aim of this study was to investigate the red blood cell (RBC) deformability and lipid peroxidation product content within erythrocytes in acute pancreatitis in rats.