Publications by authors named "Roza A"

Akamboja Roza et al., 2017 (Phengodidae: Mastinocerinae) was described to include five species, all from Atlantic Forest, which are characterized by having ten segmented antennae, biflabellate from antennomeres IV-VIII, and with fused flabellae on antennomere IX. The genus comprises six species today, including one from Ilha Grande (Angra dos Reis, Rio de Janeiro State, Brazil) with the IX antennomere flabellae not fused.

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A 41-year-old woman presented with a facial asymmetry in the mental region and a painful, well-circumscribed, tender mass in the right lower buccal vestibule, associated with extensive ill-defined bone rarefaction with subtle cortical bone resorption. Microscopically, a proliferation of bland spindle cells interspersed with collagen fibers and prominent staghorn-like blood vessels was observed. Immunohistochemical analysis revealed strong positivity for CD34, Bcl-2, CD99, and STAT-6, confirming the diagnosis of Solitary Fibrous Tumor (SFT).

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Objective: To describe the clinicopathological features of 3 new cases of soft-tissue keratocyst (STK) of the buccal mucosa from Brazil.

Materials And Methods: Clinical data from 3 patients diagnosed with STK were obtained from the archives of the Laboratory of Oral Pathology at the Federal University of Rio de Janeiro- Brazil from 2020 to 2023. Two oral pathologists reviewed conventional hematoxylin and eosin-stained slides of each case.

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Benign peripheral nerve sheath tumors (BPNSTs) are a vast, common, heterogeneous group of lesions that are often diagnostically challenging. The head and neck region is recognized as the second most common location for these lesions, especially the tongue. However, BPNSTs occurring centrally within the jaw bones are exceedingly rare.

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Cellular neurothekeoma (CN) is a benign dermal neoplasm that most often affects the head and neck region and rarely occurs in the oral mucosa. We report a rare case of CN with atypical features on the floor of the mouth and summarize the reported cases of oral CN in English-language literature. A 62-year-old woman presented with a 6-month history of a painless mass on the floor of the mouth.

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Objective: To conduct a systematic review to determine the global prevalence of HPV in oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma (OPSCC).

Materials And Methods: Literature was searched through October 2022 in main databases to address the question "What is the global prevalence of Human Papillomavirus in oral and oropharyngeal cancer?" Studies had to identify HPV by PCR, ISH, or p16 immunohistochemistry to be eligible. Quality was assessed using the JBI checklist for prevalence studies.

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Article Synopsis
  • * The study involved clinical data from five patients, mostly middle-aged men, with issues primarily in the oral mucosa; all cases showed typical symptoms and characteristics of HPV-OED.
  • * Patients received conservative surgical treatment, and after an average follow-up of 39 months, there were no signs of disease recurrence.
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Clear cell odontogenic carcinoma (CCOC) is a rare malignant odontogenic tumour (MOT) that mainly affects the mandible, with a slight female predominance in adult patients. In this study, we described an exuberant CCOC in mandible of a 22-year-female patient. On radiographic examination, a radiolucent lesion in the region of tooth 36 to 44 with tooth displacement and alveolar cortical resorption was observed.

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Purpose: The purpose of this study was to elicit the relationship of antiplatelet therapy (AP) in maintaining arteriovenous graft (AVG) patency after successful percutaneous pharmacomechanical thrombectomy ("declot").

Materials And Methods: This was an institutional review board-approved retrospective review of AVG declot procedures between July 2019 and August 2020. AVG characteristics, bleeding complications, anticoagulation and antiplatelet medication regimens, and thrombosis free survival were evaluated.

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Background: Rhabdomyosarcoma (RMS) harboring EWSR1/FUS-TFCP2 fusions has been recently described as a distinct form of RMS with an aggressive course and predilection for the craniofacial bones, especially the jaws.

Methods: We report three new cases of this rare entity, two from Brazil and one from Guatemala, with detailed clinicopathologic, immunohistochemical, and molecular descriptions. Additionally, we explored the English-language literature searching RMS with TFCP2 rearrangement or typical immunophenotype with co-expression of AE1/AE3 and ALK in the head and neck region.

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Opisthencentrus W. Horn, 1893 is a rare monotypic genus of Cicindelidae. The only species, Opisthencentrus dentipennis (Germar, 1843), was recently revised, based only on seven historical specimens, besides a recent published record.

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Objectives: The aim of the current study was to analyse the demographic, clinical and radiological features of primary aneurysmal bone cysts (ABCs) involving the maxillofacial region.

Methods: Histologically confirmed cases affecting the maxillofacial region were retrospectively reviewed over a 21-year period (2000-2021). Cases were collected from the archives of five Oral Pathology laboratories from three countries: South Africa, Guatemala and Brazil.

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Objective: The purpose of this multicenter retrospective study was to report the clinical and radiologic features of 92 glandular odontogenic cysts (GOCs) diagnosed over a 20-year period.

Study Design: Histologically confirmed cases of GOC were retrospectively reviewed from 4 oral pathology laboratories in South Africa and Brazil to categorize the clinical and radiologic spectrum of GOCs.

Results: The mean age of patients was 46 years (range 17-87) with a male-to-female ratio of 1.

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Objective: To report the clinicopathologic features of acquired oral syphilis cases in South American countries.

Materials And Methods: Clinical data were retrospectively collected from the records of 18 oral diagnostic services in Argentina, Brazil, Chile, Colombia, Venezuela, Uruguay, and Peru. Serologies of nontreponemal and treponemal tests were used for diagnosis.

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The oral lymphoepithelial cyst (OLC) is an uncommon lesion whose pathogenesis remains poorly understood. The aim of this study was to report the clinicopathologic features of the OLCs and to verify a possible association between OLCs and subgemmal neurogenous plaque (SNP) in the posterior lateral region of the tongue. A retrospective descriptive cross-sectional study was carried out.

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Article Synopsis
  • - The study focuses on the challenging diagnosis of rare oral and maxillofacial mature T/NK-cell neoplasms, highlighting their diverse characteristics and a lack of comprehensive data regarding their clinical aspects.
  • - Researchers analyzed 22 cases of mature T/NK-cell lymphomas retrieved from pathology files, confirming diagnoses through various methods and noting that the majority were extranodal NK/T-cell lymphomas and peripheral T-cell lymphomas, primarily affecting older males.
  • - The findings reveal that the palate is the most commonly impacted area, with tumors presenting as destructive and painful ulcers, and Epstein-Barr virus (EBV) was found in all cases of a specific subtype, indicating a highly aggressive nature of these neoplasms.
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The role of digital pathology in remote reporting has seen an increase during the COVID-19 pandemic. Recently, recommendations had been made regarding the urgent need of reorganizing head and neck cancer diagnostic services to provide a safe work environment for the staff. A total of 162 glass slides from 109 patients over a period of 5 weeks were included in this validation and were assessed by all pathologists in both analyses (digital and conventional) to allow intraobserver comparison.

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Objective: Calcifying odontogenic cysts (COCs) exhibit diverse clinical behaviours and may be associated with other benign odontogenic tumours. In this study, the clinical and radiological features of COCs were analysed according to subtypes based on the classification by Praetorius et al. Emphasis was placed on cases exhibiting atypical or aggressive radiological appearances.

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Article Synopsis
  • - Osteopontin (OPN) is a protein that interacts with calcium and is crucial for various bodily functions, particularly in bone cell activities and mineralization, but it also plays a role in diseases like cancer and atherosclerosis.
  • - Research indicates that OPN may contribute to the development of oral cancer by promoting aggressive cell behaviors through the PI3K/AKT/mTOR signaling pathway, which can enhance cell growth, invasion, and resistance to treatment.
  • - The text reviews the mechanisms by which OPN is involved in oral cancer and explores its potential use in clinical settings for diagnosis and prognosis of the disease.
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Objective: The aim of this study was to estimate the frequency of oral leukoplakia and oral erythroplakia in young patients.

Study Design: The systematic review was based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and performed in the following electronic databases: PubMed, Scopus, and Embase. The studies included were cross-sectional, cohort, and diagnostic, which provided with clinical and microscopic data of patients younger than 40 years.

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Objective: The aim of this study was to report the clinicopathologic features of 62 cases of central odontogenic fibroma (COdF).

Study Design: Clinical and radiographic data were collected from the records of 13 oral pathology laboratories. All cases were microscopically reviewed, considering the current World Health Organization classification of tumors and were classified according to histopathologic features.

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Article Synopsis
  • - A study was conducted to analyze the occurrence and types of pigmented lesions in the oral mucosa within a Brazilian population over a 45-year period, finding that only 0.99% of diagnosed lesions were pigmented.
  • - The study revealed that out of 761 pigmented lesions, 46.1% were melanocytic and 53.9% non-melanocytic, with a higher prevalence in females aged 40-70, and the most common lesions identified were amalgam tattoos and melanotic macules.
  • - The results are consistent with previous research, underscoring the importance of understanding oral pigmented lesions to improve diagnostic capabilities and patient management in clinical practice.
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