Publications by authors named "Roya Rezaei"
Background: Clear cell renal cell carcinoma (ccRCC) plays a significant role in the mortality associated with kidney cancer. Targeting biological processes that inhibit cancer growth opens up new treatment possibilities. The unfolded protein response (UPR) and apoptosis have crucial roles in RCC progression.
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- * Despite their potential, siRNAs face challenges such as poor cellular uptake, unintended effects on non-target genes, and degradation in the bloodstream, limiting their effectiveness as therapies.
- * The research focuses on developing advanced nanocarriers to improve siRNA delivery, addressing issues like release from endosomes and evaluating various strategies and clinical progress for siRNA-based cancer treatments.
Background: Parasporin (PS) proteins have cytocidal activity preferential for various human malignant cells. The purpose of this investigation was to see if the PS separated from B. thuringiensis strain E8 isolate had any particular cytotoxicity against breast cancer.
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