Publications by authors named "Roy Y L Lai"
Eur J Med Chem
October 2017
Article Synopsis
- Chagas disease and leishmaniasis impact over 20 million people in developing countries, with current treatments being toxic and in need of safer alternatives.
- The study synthesized 27 marine alpha-pyrones and tested their effectiveness against the parasites causing these diseases, revealing several compounds with significant antiparasitic activity.
- Among the tested compounds, one (3-tetradecanoyl pyrone) showed promising results in reducing T. cruzi infection in mice while demonstrating no toxic effects.
