Publications by authors named "Roxana D Pasca"
Articular cartilage has a complex structure and metabolism which allow for a proper movement within joints. Nevertheless, several systemically administered pharmacological agents have been proved to improve the anabolic response in the case of cartilage lesions. Alendronate, glucosamine, chondroitin sulfate, hyaluronic acid, collagen hydrolysate, vitamin C, vitamin D, aspirin and strontium ranelate have shown positive results in clinical trials.
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- Silver nanoparticles (AgNPs) were created by reducing silver ions with glucose in a basic solution and were stabilized using tetraethyl orthosilicate and L-asparagine.
- The AgNPs were characterized for their properties and interactions with local anesthetics (procaine, dibucaine, and tetracaine), showing changes in optical spectra that indicate the formation of assemblies influenced by the anesthetics.
- Techniques such as zeta-potential measurements and electron microscopy were used to analyze the size, shape, and stability of the nanoparticles, highlighting the role of electrostatic, hydrophobic, and hydrogen bonding interactions between AgNPs and anesthetic molecules.