Publications by authors named "Rowan F AlEjielat"
Background: Previous studies have shown the central role of 78 kDa glucose-regulated protein (GRP78) in colorectal cancer (CRC) survival and chemoresistance. In the present study, we aimed to design a GRP78 inhibitor and test its potential to inhibit CRC cells growth.
Materials And Methods: Computer-aided drug design was used to establish novel compounds as potential inhibitors of GRP78.