Could 3D placental volume and perfusion indices measured at 11-14 weeks predict occurrence of preeclampsia in high-risk pregnant women?

Objective: Preeclampsia (PE) is a known cause of maternal, fetal and neonatal morbidity and mortality. Thus, evaluation of the predicting value of combining the 3D assessment of placental volume with the assessment of placental perfusion indices through 3D power Doppler (3DPD) at 11-14 weeks in pregnant women at high risk to develop PE could be a suitable screening method.

Methods: 3D assessment of placental volume and 3DPD assessment of placental vascularization indices at 11-13 weeks and uterine artery Doppler scan (RI and PI) at 21-22 weeks were conducted in this prospective case-control study.