Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

Cancer cells are exposed to major compressive and shearing forces during invasion and metastasis, leading to extensive plasma membrane damage. To survive this mechanical stress, they need to repair membrane injury efficiently. Targeting the membrane repair machinery is thus potentially a new way to prevent invasion and metastasis.

[Simulation, a pedagogical method appreciated by student nurses].

Simulation is a pedagogical method frequently used in nurse training institutes. It uses ever-more sophisticated tools and equipment to reflect as closely as possible real-life situations. Feedback gathered from student nurses in the Grand Est region shows that their experience of these innovative approaches in initial training is positive.