Proc Natl Acad Sci U S A
October 2024
Algae populate multiple habitats, including snow and ice, where they can form red blooms. These decrease snow albedo, accelerating snowmelt and potentially feeding back on snow and glacier decline caused by climate change. Quantifying this feedback requires the understanding of bloom evolution with climate change.
View Article and Find Full Text PDFPurpose: Social eating (SE) is a corner stone of daily living activities, quality of life (QoL), and aging well. In addition to feeding functional disorders, patients with head and neck cancer (HNC) face individual and social psychological distress. In this aging population, we intended to better assess the influence of age on these challenges, and the role of self-stigmatization limiting SE in patients with and beyond HNC.
View Article and Find Full Text PDFJ Gynecol Obstet Hum Reprod
November 2024
Background: Uterine incarceration is a rare complication of pregnancy. The most frequent complications are pain and urinary retention.
Case: We present the case of a patient who had presented a uterine incarceration during her first pregnancy, requiring a reduction under general anesthesia at 27 weeks of gestation complicated by premature delivery at 29 weeks of gestation.
Background: Cosmetic plastic surgery in the United States is underutilized by African American and Hispanic populations compared with their White and Asian counterparts. This study evaluated whether microeconomic spending traits as a representation of financial stability can inform trends in cosmetic procedure volumes by racial group.
Methods: Annual volumes for the top five cosmetic surgical and cosmetic minimally invasive procedures by racial/ethnic group from 2012 to 2020 were collected from the American Society of Plastic Surgeons' annual reports.
Glioblastoma is a highly heterogeneous and infiltrative form of brain cancer associated with a poor outcome and limited therapeutic effectiveness. The extent of the surgery is related to survival. Reaching an accurate diagnosis and prognosis assessment by the time of the initial surgery is therefore paramount in the management of glioblastoma.
View Article and Find Full Text PDFTears of the gluteus medius and minimus are an important cause of recalcitrant greater trochanteric pain syndrome. Although endoscopic and open abductor repairs have demonstrated promising outcomes, the success of these techniques is dependent on the size of the tear and the quality of the tissue. In patients presenting with abductor insufficiency and evidence of previous repair failure, large retracted tears, muscle atrophy and/or fatty infiltration, reconstruction/augmentation techniques should be considered.
View Article and Find Full Text PDFProgress in skull-base endoscopic surgery has improved our knowledge of olfactory cleft (OC) anatomy. This article presents a review of current knowledge concerning the OC roof: descriptive anatomy, radiological exploration, and endoscopic observation. The OC is a narrow area in the most superior part of the nasal cavity.
View Article and Find Full Text PDFOvarian cancer is the leading cause of death from gynecologic cancer worldwide. High-grade serous carcinoma (HGSC) is the most common and deadliest subtype of ovarian cancer. While the origin of ovarian tumors is still debated, it has been suggested that HGSC originates from cells in the fallopian tube epithelium (FTE), specifically the epithelial cells in the region of the tubal-peritoneal junction.
View Article and Find Full Text PDFAutosomal recessive tyrosine kinase 2 (TYK2) deficiency is characterized by susceptibility to mycobacterial and viral infections. Here, we report a 4-year-old female with severe respiratory viral infections, EBV-driven Burkitt-like lymphoma, and infection with the neurotropic Jamestown Canyon virus. A novel, homozygous c.
View Article and Find Full Text PDFBackground: In 2018, the City of Providence introduced a program in which electronic scooters were deployed for public use. We aim to characterize the burden of craniofacial injuries associated with these scooters.
Methods: A retrospective review was conducted of all patients consulted to the plastic surgery service for evaluation of craniofacial injury between September 2018 and October 2022.
Head and neck (HN) squamous cell carcinomas (SCCs) originate from the epithelial cells of the mucosal linings of the upper aerodigestive tract, which includes the oral cavity, the pharynx, the larynx, and the sinonasal cavities. There are many associated risk factors, including alcohol drinking coupled with tobacco use, which accounts for 70% to 80% of HNSCCs. Human papilloma virus (HPV) is another independent risk factor for oropharyngeal SCC, but it is only a minor contributor to oral cavity SCC (OSCC).
View Article and Find Full Text PDFNurs Clin North Am
December 2022
Professional burnout is a significant occupational hazard resulting in lower job commitment, poor patient outcomes, reduced performance, lower job satisfaction, and frequent absenteeism. Models exist that provide guidance in addressing burnout, improving resiliency, and well-being. Advancing evidence-based, multidisciplinary solutions to improve patient care by caring for the caregiver is the cornerstone to increasing resiliency, well-being, empathy, and gratitude.
View Article and Find Full Text PDFBackground: AACN published a clarifying document in 2015 to guide Doctor of Nursing Practice (DNP) programs' DNP Scholarly Projects. This publication provided specific and general guidance; however, areas of inconsistent interpretation remained. The variability of best practices for DNP projects sparked the idea for a national survey to explore how projects are being carried out and to determine if the varied approaches align with AACN's 2015 recommendations.
View Article and Find Full Text PDFBackground: Concern has been raised related to the rigor of DNP team projects due to the potential lack of individual opportunity for growth. However, team science, the scientific collaboration conducted by more than one individual in an interdependent fashion, is becoming standard practice for scientific inquiry and dissemination. DNP team projects provide an opportunity to demonstrate competencies related to collaboration, communication, organization, planning, reliability, accountability and acknowledgement of other opinions, expertise, and contributions.
View Article and Find Full Text PDFPurpose: We investigated whether artificial intelligence (AI)-based denoising halves PET acquisition time in digital PET/CT.
Methods: One hundred ninety-five patients referred for [F]FDG PET/CT were prospectively included. Body PET acquisitions were performed in list mode.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ∼20% of deceased patients across age groups, and in ∼1% of individuals aged <70 y and in >4% of those >70 y old in the general population. With a sample of 1,261 unvaccinated deceased patients and 34,159 individuals of the general population sampled before the pandemic, we estimated both IFR and relative risk of death (RRD) across age groups for individuals carrying autoantibodies neutralizing type I IFNs, relative to noncarriers.
View Article and Find Full Text PDFBackground: The use of COVID-19 vaccines has been prioritised to protect the most vulnerable-notably, older people. Because of fluctuations in vaccine availability, strategies such as delayed second dose and heterologous prime-boost have been used. However, the effectiveness of these strategies in frail, older people are unknown.
View Article and Find Full Text PDFEthical and legal considerations have led to increased use of non-animal methods to evaluate the safety of chemicals for human use. We describe the development and qualification of a physiologically-based kinetics (PBK) model for the cosmetic UV filter ingredient, homosalate, to support its safety without the need of generating further animal data. The intravenous (IV) rat PBK model, using PK-Sim, was developed and validated using legacy data generated prior to the 2013 EU animal-testing ban.
View Article and Find Full Text PDFSARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across age groups. In the general population, they are found in ~1% of individuals aged 20-70 years and in >4% of those >70 years old.
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