This study presents an efficient and environmentally sustainable synthesis of ZnO nanoparticles using a starch-mediated sol-gel approach. This method yields crystalline mesoporous ZnO NPs with a hexagonal wurtzite structure. The synthesized nanoparticles demonstrated remarkable multifunctionality across three critical applications.
View Article and Find Full Text PDFObjective: to present the epidemiological, diagnostic, therapeutic and progressive aspects of laryngeal papillomatosis.
Patients And Method: This was a retrospective study over a period of 6 years (January 2016 to December 2021), covering cases of laryngeal papillomatosis collected at the Oto-Rhino-Laryngology department of the Niamey National Hospital.
Results: A total of 36 cases of laryngeal papillomatosis were recorded.
Objective: To evaluate the surgical management of thyroid pathologies at the Reference General Hospital.
Methods: This was a retro-prospective study over 4 years 6 months carried out in the departments of General and Digestive Surgery (GDS) and Otorhinolaryngology and Cervico Facial Surgery (ORL/FCS). It involved 182 patients who underwent thyroid surgery.
Tyrosinase is a key enzyme in the biosynthesis of melanin, which is responsible for the browning of foods as well as many skin disorders. In order to develop new anti-browning agents with dual antioxidant and anti-tyrosinase capacities, a series of 30 thiazolyl hydrazone derivatives were synthesized. Among the molecules prepared, 6 and 30 were found to be the most potent tyrosinase inhibitors with IC values comparable to that of kojic acid.
View Article and Find Full Text PDFThe antiradical capacity and mechanisms of two representative coumestan-type compounds, namely isosojagol () and phaseoul (), were examined using quantum chemistry calculations and computational kinetics methods. From a thermodynamic point of view, the 18CH groups of the prenyl substituent have been found to be the most suitable sites for radical attacks the formal hydrogen transfer (FHT) mechanism. However, the kinetic study revealed that the reaction at these CH groups is slow and does not contribute to the overall reactivity of these compounds, which the phenolic groups mainly define.
View Article and Find Full Text PDFTacrine, the first drug approved for the treatment of Alzheimer's disease (AD), is a non-competitive cholinesterase inhibitor withdrawn due to its acute hepatotoxicity. However, new non-hepatotoxic forms of tacrine have been actively researched. Moreover, several recent reports have shown that oxidative stress is the cause of damage and plays a role in the pathogenesis of several neurodegenerative diseases including AD.
View Article and Find Full Text PDFPenetrating neck and facial injuries are rare withonly a few cases reported in literature. Indeed, they are extremely rare in developed countries but remain relevant in our rural areas that are characterized by the recurrence of intertribal clashes. It was in thiscontextthatwereceivedtwo patients in the department of ENT of Niamey National Hospital.
View Article and Find Full Text PDFEur Ann Otorhinolaryngol Head Neck Dis
June 2011
Introduction: We report a case of cervical Pott's disease revealed by parapharyngeal abscess.
Case Report: A seven-year-old boy was admitted with a three-week history of painful fluctuating left lateral cervical swelling, associated with night sweats. Examination found trismus, through which a lateral pharyngeal bulge could be observed.
Objective: To illustrate the rarity and difficulty diagnosing maxillary sinus neurofibroma through a case report.
Patients And Methods: A 35-year-old female consulted our department for left cheek swelling evolving over 6 months, upper gum swelling, and a dental occlusion disorder.
Results: A computed tomography scan showed a tumor of the left maxillary sinus with bone destruction.