Publications by authors named "Rouhollah Ameri"
J Ophthalmic Vis Res
September 2024
Article Synopsis
- Sulfur mustard (SM) is a harmful chemical that causes serious eye damage, and the study focuses on comparing the anti-inflammatory effects of curcumin and doxycycline in treating corneal injuries induced by a similar agent, CEES.
- The research utilized the HCE-2 cell line to assess effective concentrations and measure changes in gene expression and activity of MMP-2 and MMP-9 enzymes after treatment.
- Results showed that both curcumin and doxycycline reduced MMP expression and activity, with curcumin demonstrating a stronger effect on MMP-9 compared to doxycycline, suggesting potential use as anti-inflammatory treatments for chemical eye injuries.
