Increased androgen secretion in patients with prolactinomas: the impact of altered HPA function.

Background And Objectives: Earlier studies suggested that hyperprolactinemia was associated with elevated serum DHEA-S levels. The importance of DHEA-S measurements in the diagnosis of adrenal insufficiency prompted us to assess adrenal androgen levels in hyperprolactinemic subjects with normal or impaired function.

Methods: Prospective study including 122 medically treated and 26 surgically patients with prolactinomas.