Do More Expensive Total Knee Arthroplasty Prostheses Provide Greater Improvements in Outcomes Over Less Expensive Prostheses Sold by a Physician-owned Distributorship?

Background: It is unknown whether more expensive total knee prostheses provide better improvements in patient-determined outcomes compared with less expensive prostheses. A physician-owned distributorship (POD) was created with a goal to provide lower cost implants to hospitals as an alternative to higher cost prostheses sold by the large orthopaedic implant companies. The hypothesis was that lower cost total knee prostheses would have equivalent outcomes, while resulting in lower costs to the hospitals purchasing them compared with higher cost industry-supplied knee prostheses.

Evaluation of Methods to Quantify Populations of Rhizoctonia in Soil.

The best method to quantitatively determine populations of Rhizoctonia in soil from soybean fields undergoing rice and soybean rotations was determined for use in a large-scale spatial study to be done over multiple fields and years. The methods evaluated were the toothpick-baiting method, the multiple-pellet soil sampler, and the pour-plate method using elutriated organic matter from soil or surface residue. The toothpick-baiting method was calibrated using the multiple-pellet soil sampler and determined to assay an approximate soil volume of 15.

Soil Texture Influence on Meloidogyne incognita and Thielaviopsis basicola and Their Interaction on Cotton.

Microplots were used to evaluate the impact of soil texture on Meloidogyne incognita, Thielaviopsis basicola, and their interaction on cotton. A native silt loam soil (48% sand) and four different artificial soil textures produced by mixing native soil with sand (53, 70, 74, and 87% sand) were studied. Each soil texture was infested with 0, 4, or 8 M.

Effects of Meloidogyne incognita and Thielaviopsis basicola on cotton growth and root morphology.

Effects of the root-knot nematode Meloidogyne incognita and the fungal pathogen Thielaviopsis basicola on cotton seedling growth and root morphology were evaluated in controlled environmental experiments. Four pathogen treatments, including noninfested soil, soil infested with M. incognita, soil infested with T.

Effects of Soil Compaction and Meloidogyne incognita on Cotton Root Architecture and Plant Growth.

The effects of a soil hardpan and Meloidogyne incognita on cotton root architecture and plant growth were evaluated in microplots in 2010 and 2011. Soil was infested with M. incognita at four different levels with or without a hardpan.

Effect of Fungicide Seed Treatments, Cultivars, and Soils on Soybean Stand Establishment.

Seedling diseases are one of the major production problems for soybean. The primary control of soybean seedling diseases is by fungicide seed treatments but comparisons of seed treatments are difficult because stand responses are often erratic in the field. The objective of this study was to determine the efficacy of soybean fungicide seed treatments in naturally infested soils under controlled environments at three temperatures.

Surgical management for malignant tumors of the thumb.

Background: Malignant tumors of the thumb can be treated surgically with either wide local excision with reconstruction or amputation. Local excision of tumors in the thumb and hand often requires closer resection margin than at other sites, and there is also a need for tissue transfer from a donor site for reconstruction. Primary thumb amputation allows local tumor control while avoiding donor-site morbidity, but comes at great functional cost.

Importance of Fungicide Seed Treatment and Environment on Seedling Diseases of Cotton.

The importance of fungicide seed treatments on cotton was examined using a series of standardized fungicide trials from 1993 to 2004. Fungicide seed treatments increased stands over those from seed not treated with fungicides in 119 of 211 trials. Metalaxyl increased stands compared to nontreated seed in 40 of 119 trials having significant fungicide responses, demonstrating the importance of Pythium spp.

RETRACTED: Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment.

Tumors induce new blood vessel growth primarily from host organ microvascular endothelial cells (EC), and microvasculature differs significantly between the lung and liver. Vascular endothelial growth factor (VEGF or VEGF-A) promotion of tumor angiogenesis is thought to be mediated primarily by VEGF receptor-2 (VEGFR-2). In this study, VEGFR-2 antibody (DC101) inhibited growth of RenCa renal cell carcinoma lung metastases by 26%, whereas VEGFR-1 antibody (MF-1) had no effect.

Phase II study of neoadjuvant bevacizumab and radiotherapy for resectable soft tissue sarcomas.

Purpose: Numerous preclinical studies have demonstrated that angiogenesis inhibitors can increase the efficacy of radiotherapy (RT). We sought to examine the safety and efficacy of bevacizumab (BV) and RT in soft tissue sarcomas and explore biomarkers to help determine the treatment response.

Methods And Materials: Patients with ≥5 cm, intermediate- or high-grade soft tissue sarcomas at significant risk of local recurrence received neoadjuvant BV alone followed by BV plus RT before surgical resection.

First Report of Black Root Rot Caused by Thielaviopsis basicola on Soybean (Glycine max) in Arkansas.

Thielaviopsis basicola (Berk. & Broome) Ferraris (synonym Chalara elegans Nag Raj & Kendrick) is a soilborne plant-pathogenic fungus reported in many parts of the world. In Arkansas, T.

RETRACTED: Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1.

Metastasis relies on angiogenesis for tumor expansion. Tumor angiogenesis is restrained by a variety of endogenous inhibitors, including thrombospondin 1 (TSP1). The principal antiangiogenic activity of TSP1 resides in a domain containing three TSP1 repeats (3TSR), and TSP1 cleavage is regulated, in part, by the metalloproteinase ADAMTS1.

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.

Purpose: Sunitinib (SU) is a multitargeted receptor tyrosine kinase inhibitor of the vascular endothelial growth factor and platelet-derived growth factor receptors. The present study examined SU and radiotherapy (RT) in a genetically engineered mouse model of soft tissue sarcoma (STS).

Methods And Materials: Primary extremity STSs were generated in genetically engineered mice.

Efficacy of Seed Treatment Chemicals for Black Root Rot, Caused by Thielaviopsis basicola, on Cotton.

The efficacy of triazole and host resistance-inducing seed treatment chemicals was examined for black root rot on cotton caused by Thielaviopsis basicola in both artificially and naturally infested soils with and without nematodes. In naturally infested soil, myclobutanil was effective in reducing root and hypocotyl discoloration over a wide range of soil population densities. Treatments containing high rates (42 g a.

Effect of Temperature on and Histopathology of the Interaction Between Meloidogyne incognita and Thielaviopsis basicola on Cotton.

ABSTRACT Controlled environments were used to study the relationship between the root-knot nematode (Meloidogyne incognita) and Thielaviopsis basicola on cotton. Temperature treatments were continuous 20, 24, and 28 degrees C or two cyclic linear regimes with ranges of 14 to 32 or 18 to 28 degrees C over 24 h. Cotton seeds were planted in fumigated soil infested with T.

Resistance of the Soybean Cultivar Archer to Pythium Damping-Off and Root Rot Caused by Several Pythium spp.

Archer, a maturity group I soybean cultivar with demonstrated flood tolerance and resistance to Pythium ultimum, was compared with Hutcheson, a widely planted maturity group V cultivar in Arkansas, for resistance to P. ultimum, P. irregulare, P.

Twelve-year follow-up on anterior cruciate ligament reconstruction: long-term outcomes of prospectively studied osseous and articular injuries.

Background: Although successful at restoring near normal laxity to the knee in the short term, anterior cruciate ligament reconstructions have not been shown to prevent the development of posttraumatic arthritis.

Hypothesis: Bone bruises and articular cartilage injuries sustained at the time of initial injury (1991) would not resolve. Our secondary hypothesis was that the presence of a bone bruise or articular cartilage injury originally identified on magnetic resonance imaging would not be associated with long-term outcomes after anterior cruciate ligament reconstruction evaluated by the International Knee Documentation Committee questionnaire.

Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.

Purpose: Thrombospondin-1 (Tsp1), endostatin, and tumstatin are extracellular matrix-associated proteins that inhibit angiogenesis. We examined the mechanisms by which tumor cells may bypass the antiangiogenic effects of these endogenous regulators.

Experimental Design: CT26 colon and RenCa renal carcinoma cells were stably transfected with Tsp1, endostatin, or tumstatin cDNA.

Potential for Site-specific Management of Meloidogyne incognita in Cotton Using Soil Textural Zones.

The effect of various edaphic factors on Meloidogyne incognita population densities and cotton yield were evaluated from 2001 to 2003 in a commercial cotton field in southeastern Arkansas. The 6.07-ha field was subdivided into 512 plots (30.

The Effect of Pythium ultimum and Soil Flooding on Two Soybean Cultivars.

The effect of flooding and Pythium ultimum on soybean, Glycine max, was determined in a series of greenhouse experiments using the cultivars Hutcheson and Archer. Seeds were planted into pasteurized soil either not infested or infested with sand-cornmeal inoculum of P. ultimum and either flooded at emergence for 2 days or at the four leaf node stage (V4) for 5 days.