What does metaphoric language say about aggression? The relationships between metaphoric language, impulsivity, and aggression.

Aggressive behavior among adolescents has been identified as a serious worldwide problem, especially when combined with trait impulsivity. This study investigates the impact of an overlooked aspect of language, namely, metaphor comprehension, on impulsivity and aggression in adolescents. A total of 204 adolescents completed self-reported questionnaires assessing impulsivity and aggression and underwent tests assessing familiar and less familiar metaphor comprehension.

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.

Resistance mechanisms to immune checkpoint blockade therapy (ICBT) limit its response duration and magnitude. Paradoxically, Interferon γ (IFNγ), a key cytokine for cellular immunity, can promote ICBT resistance. Using syngeneic mouse tumour models, we confirm that chronic IFNγ exposure confers resistance to immunotherapy targeting PD-1 (α-PD-1) in immunocompetent female mice.

Personality traits and environment: The effects of observing visual art on verbal creativity.

Figurative language is one of the most prevalent expressions of verbal creativity, and use of novel metaphors is the most significant source of verbal innovation. As environmental and personality trait factors can impact creativity, the current study aimed to examine whether exposure to an environment rich in visual stimuli (artwork) and verbal stimuli (novel metaphors) contributes to verbal creativity, taking into account the personality trait of "openness to experience." Study participants (132) were divided into three groups: (1) a group exposed to a creative verbal environment (reading novel metaphors), (2) a group exposed to a visually creative environment (observing abstract and figurative artwork), and (3) a group not exposed to any creative environment.

Tackling the Electro-Topography of the Selves Through the Sphere Model of Consciousness.

In the current hypothesis paper, we propose a novel examination of consciousness and self-awareness through the neuro-phenomenological theoretical model known as the Sphere Model of Consciousness (SMC). Our aim is to create a practical instrument to address several methodological issues in consciousness research. We present a preliminary attempt to validate the SMC a simplified electrophysiological topographic map of the Self.

Processing of Emotions in Speech in Forensic Patients With Schizophrenia: Impairments in Identification, Selective Attention, and Integration of Speech Channels.

Individuals with schizophrenia show deficits in recognition of emotions which may increase the risk of violence. This study explored how forensic patients with schizophrenia process spoken emotion by: (a) identifying emotions expressed in prosodic and semantic content separately, (b) selectively attending to one speech channel while ignoring the other, and (c) integrating the prosodic and the semantic channels, compared to non-clinical controls. Twenty-one forensic patients with schizophrenia and 21 matched controls listened to sentences conveying four emotions (anger, happiness, sadness, and neutrality) presented in semantic or prosodic channels, in different combinations.

Trait impulsivity and callous-unemotional traits as predictors of inhibitory control and risky choices among high-risk adolescents.

Trait impulsivity and callous-unemotional traits are associated with behavioural problems among high-risk adolescents. While both are known to influence behaviour, the nature of their expression in high-risk behaviours, particularly those related to inhibitory control, is not well understood. In the current, preliminary study, we examined whether and how these traits predicted deficits in behaviour driven by bottom-up, automatic versus deliberate, top-down inhibitory processes among high-risk adolescents.

The Implications of Motor and Cognitive Inhibition for Hot and Cool Executive Functions: The Case of Quadrato Motor Training.

Enabling the ceasing of ongoing or prepotent responses and the controlling of interference, motor inhibition facilitates the development of executive functions (EFs) such as thought before action, decision-making, self-regulation of affect, motivation, and arousal. In the current paper, a characterization is offered of the relationship between motor inhibition and the executive functioning system, in the context of a proposed division into predominantly affective (hot) and cognitive (cool) components corresponding to neural trajectories originating in the prefrontal cortex. This division is central to understanding the effects of a specifically-structured sensorimotor movement training practice, known as Quadrato Motor Training (QMT), on hot and cool EFs.

Elucidating the role of selective attention, divergent thinking, language abilities, and executive functions in metaphor generation.

Metaphoric language is one of the most common expressions of creative cognition in everyday life. However, the cognitive mechanisms underlying metaphor generation remain largely unexplained. In this study, we aimed to investigate the relationship between various cognitive functions and both novel and conventional metaphor generation.

Creating an Internal Environment of Cognitive and Psycho-Emotional Well-Being through an External Movement-Based Environment: An Overview of Quadrato Motor Training.

In this overview, we discuss the internal and external environmental factors associated with cognitive and psycho-emotional well-being in the context of physical activity and Mindful Movement. Our key argument is that improved cognitive and emotional functions associated with mental well-being can be achieved by an external, Mindful Movement-based environment training called Quadrato Motor Training (QMT). QMT is a structured sensorimotor training program aimed at improving coordination, attention, and emotional well-being through behavioral, electrophysiological, neuroanatomical, and molecular changes.

Does emotion matter? The role of alexithymia in violent recidivism: A systematic literature review.

Background: Several variables have been evidenced for their association with violent reoffending. Resultant interventions have been suggested, yet the rate of recidivism remains high. Alexithymia, characterised by deficits in emotion processing and verbal expression, might interact with these other risk factors to affect outcomes.

Using Dual Process Models to Examine Impulsivity Throughout Neural Maturation.

The multivariate construct of impulsivity is examined through neural systems and connections that comprise the executive functioning system. It is proposed that cognitive and behavioral components of impulsivity can be divided into two distinct groups, mediated by (1) the cognitive control system: deficits in top-down cognitive control processes referred to as action/cognitive impulsivity and (2) the socioemotional system: related to bottom-up affective/motivational processes referred to as affective impulsivity. Examination of impulsivity from a developmental viewpoint can guide future research, potentially enabling the selection of more effective interventions for impulsive individuals, based on the cognitive components requiring improvement.

Relationships between trait impulsivity and cognitive control: the effect of attention switching on response inhibition and conflict resolution.

This study examined the relationship between trait impulsivity and cognitive control, as measured by the Barratt Impulsiveness Scale (BIS) and a focused attention dichotic listening to words task, respectively. In the task, attention was manipulated in two attention conditions differing in their cognitive control demands: one in which attention was directed to one ear at a time for a whole block of trials (blocked condition) and another in which attention was switched pseudo-randomly between the two ears from trial to trial (mixed condition). Results showed that high impulsivity participants exhibited more false alarm and intrusion errors as well as a lesser ability to distinguish between stimuli in the mixed condition, as compared to low impulsivity participants.

The effects of sad prosody on hemispheric specialization for words processing.

This study examined the effect of sad prosody on hemispheric specialization for word processing using behavioral and electrophysiological measures. A dichotic listening task combining focused attention and signal-detection methods was conducted to evaluate the detection of a word spoken in neutral or sad prosody. An overall right ear advantage together with leftward lateralization in early (150-170 ms) and late (240-260 ms) processing stages was found for word detection, regardless of prosody.

A critical look at the relationship between impulsivity and decision-making in adolescents: are they related or separate factors?

This study examined the relations between impulsivity and decision-making as assessed by the Iowa Gambling Task (IGT). A total of 73 nonclinical adolescents were administered self-report measures for trait impulsivity and the Wisconsin Card Sorting Test (WCST) to assess cognitive impulsivity. We found significant correlations between trait impulsivity and WCST performance among adolescents exhibiting poor performance on the IGT, and no such correlations for those adolescents performing well on the IGT.

The effect of nondialyzable material (NDM) cranberry extract on formation of contact lens biofilm by Staphylococcus epidermidis.

Purpose: To assess the effects of NDM from cranberries on Staphylococcus epidermidis biofilm formed on soft contact lenses.

Methods: Soft contact lenses were incubated in Tryptic Soy Broth (TSB) together with S. epidermidis (ATCC35984/RP62A) and various concentrations of NDM, and inspected by scanning electron and confocal microscopy.

Impulsive decision-making: learning to gamble wisely?

A decade ago, Bechara et al. [Bechara, A., Damasio, A.