Publications by authors named "Rotem Gvili"
Article Synopsis
- Dendritic cells (DC) are essential immune cells that connect the body's innate and adaptive immune responses, with two main types: plasmacytoid DC (pDC) and conventional DC (cDC).
- Research using in vivo deuterium-glucose labeling revealed that a specific subset of cDC known as AXL+ Siglec6+ DC (ASDC) circulates in the bloodstream for about 2.16 days, while other cDC types have slightly shorter lifespans.
- The study also showed that ASDC are quickly recruited to inflamed areas, highlighting their role in managing immune responses during inflammation and suggesting new insights into the behavior of different DC subsets.
Dendritic cells (DCs) enable the immune system to mount and modulate precisely targeted responses to various threats across the organism by bridging innate and adaptive immunity. Historically, DCs have been classified as conventional (cDC) and plasmacytoid (pDC). More recently, cDCs were acknowledged as a heterogenous population composed of several subsets.
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