Publications by authors named "Rotaru O"

Introduction: Thrombocytopenia affects about 10% of all pregnancies. Preeclampsia/HELLP syndrome induced thrombocytopenia may associate perinatal morbidity, preterm delivery, or low-birth-weight newborns.

Objective: To assess perinatal outcome and complications of pregnancy in women presenting with thrombocytopenia.

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The acute and subchronic oral toxicities of 4 organotin derivatives were investigated in chickens. The LD50 values oscillated between 200 and 400 mg/kg bw and revealed a moderate or weak toxicity. Subchronic dosing with 2 doses from each compound at 2 and 10 mg/kg bw induced dose-dependent lesions seen at necropsy and histologic examinations.

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Malignant melanomas in 5 horses, 1 calf, 1 cow and 2 pigs were described. The disease, in white or gray horses, was tegumentally located and generalized in the organs of the abdominal cavity. Microscopically, dendritic and fusiform pigment cells and multinucleated cells were identified.

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Toxoplasmosis was clinically diagnosed in two dogs of 4 and respectively 18 months. A seven-day treatment remained inefficient and the animals died. Autopsy revealed a global inflammation of the lung, with necrotic lesions of bronchial lymph nodes and acute hyperplastic reaction of the spleen.

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Present knowledge of aetiopathogenesis of uterus fibroma is based on clinical observation and backed up by pathologico-anatomic laboratory studies. In some cases, tumours were experimentally induced to animals by oestrogenic stimulation. -- The vascular factor was considered to be of minor and unspecific importance to fibroma genesis, in the context of findings so far obtained.

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