Revealing the environmental pollution of two estuaries through histopathological biomarkers in five fishes from different trophic guilds of northeastern Brazil.

Estuaries in Brazil are mostly anthropically affected due to the discharge of industrial and domestic effluents. In two of them, the Santa Cruz Channel Estuary (ITAP) and Sirinhaém River Estuary (SIR), historically affected by mercury pollution and sugarcane industry in Northeast Brazil, we assessed environmental pollution using liver and gill histopathological biomarkers in fish from different trophic levels. Liver samples exhibited serious damages such as hepatic steatosis, necrosis, and infiltration.

The legacy of artisanal gold mining and its impact on fish health from Tapajós Amazonian region: A multi-biomarker approach.

Tapajós Region, is an area with intense historical artisanal and small-scale gold mining. Therefore, the core objective of this study was to evaluate the environmental status of different rivers located in this region, using biomarker endpoints in Serrasalmus rhombeus as a tool. Fish and sediment were collected from two rivers, Tropas and Crepori, affluent of Tapajós River, located inside a Federal Protection Area and in a Reference site.

Andiroba oil and nanoemulsion (Carapa guianensis Aublet) reduce lesion severity caused by the antineoplastic agent doxorubicin in mice.

Doxorubicin (DOX) is an anthracycline antibiotic used in the fight against many types of cancer. Although it is quite effective for this purpose, its clinical use is limited by its severe side effects, highlighting the relevance of efforts to identify substances that act to minimize these effects. In this work, we sought to verify the ability of andiroba oil (AO) and a nanoemulsion of andiroba oil (AN) to lessen the side effects of DOX.

Evaluation of metal contamination effects in piranhas through biomonitoring and multi biomarkers approach.

The present field study aimed to assess the water quality of the Itacaiúnas River, located at the eastern part of the Brazilian Amazon, using water's physicochemical parameters, ecological risk assessment in sediments, biomarkers and metal bioaccumulation in piranhas at two points: upstream (P1) and downstream (P2), and the type of season (Dry and Rainy). We revealed a significant difference between the points and the seasons. Concerning, the concentration of metals (Cd, Cu, Zn, Cr, and Hg) in sediment and water, we reported significant concentrations of Cd and Cu especially on P2 at dry season.