Publications by authors named "Ross Osborne Smith"
Int J Mol Sci
October 2022
Article Synopsis
- Cerebral cavernous malformation (CCM) is a rare neurovascular condition affecting about 0.5% of people, with recent research shifting focus from genetic causes to the role of the hemostatic system and neuroinflammation in its severity.
- This review highlights the interactions between endothelial cells lacking CCM and blood components, demonstrating how endothelial dysfunction can lead to issues like bleeding, hypoxia, and neurological symptoms.
- The findings suggest a need to view CCM as a hemostatic disease, which could influence future treatment approaches.
