Publications by authors named "Rosita Shah"

While idiopathic pulmonary fibrosis (IPF) is the most common type of fibrotic lung disease, there are numerous other causes of pulmonary fibrosis that are often characterized by lung injury and inflammation. Although often gradually progressive and responsive to immune modulation, some cases may progress rapidly with reduced survival rates (similar to IPF) and with imaging features that overlap with IPF, including usual interstitial pneumonia (UIP)-pattern disease characterized by peripheral and basilar predominant reticulation, honeycombing, and traction bronchiectasis or bronchiolectasis. Recently, the term has been used to describe non-IPF lung disease that over the course of a year demonstrates clinical, physiologic, and/or radiologic progression and may be treated with antifibrotic therapy.

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Coronavirus disease (COVID-19) is an illness caused by a novel coronavirus that has rapidly escalated into a global pandemic leading to an urgent medical effort to better characterize this disease biologically, clinically, and by imaging. In this review, we present the current approach to imaging of COVID-19 pneumonia. We focus on the appropriate use of thoracic imaging modalities to guide clinical management.

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COVID-19 is an illness caused by a novel coronavirus that has rapidly escalated into a global pandemic leading to an urgent medical effort to better characterize this disease biologically, clinically and by imaging. In this review, we present the current approach to imaging of COVID-19 pneumonia. We focus on the appropriate utilization of thoracic imaging modalities to guide clinical management.

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Objectives: To identify features of obstructive airway disease on sagittal reconstruction, compare the accuracy of findings to traditional imaging characteristics of COPD, and determine the fraction of additional cases identified using new characteristics.

Methods: The study was approved by the centre's Institutional Review Board and is HIPAA compliant. Two hundred sixteen patients with HRCT and spirometry within a 3-month window were included.

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Despite little supportive evidence, ground-glass opacity at high-resolution computed tomography, without other signs of fibrosis, has been equated with potentially reversible disease, and in systemic sclerosis, frequently prompts aggressive anti-inflammatory treatment to prevent pulmonary fibrosis. Our study evaluates ground-glass opacity on sequential high-resolution computed tomography in 41 patients with systemic sclerosis over a mean follow-up period of 27 months (r6 to 60 mo). Ground-glass opacity was the most common imaging finding, present in 66%, and usually associated with other signs of interstitial disease, including nonfibrotic interstitial opacities in 27% and fibrotic interstitial opacities in 32%.

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The aim of this article is to clarify radiographic definitions associated with common parenchymal patterns encountered in the transplant population and to discuss the most common pathologic causes responsible for each pattern. The article also touches on radiographic findings signifying complications of other intrathoracic structures, including the airways, pleural space, and mediastinum.

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Our purpose is to correlate thin section CT of peripheral bronchogenic carcinomas with histologically detected lymphatic or vascular invasion. Retrospective 3-year database search revealed 186 surgical resections for primary bronchogenic carcinoma, of which 58 had available preoperative imaging performed at our institution. Cases with prior surgery, nonconfirmatory pathology, remote imaging, or central location were excluded, resulting in a study population of 42 patients, 25 men, 17 women, with a mean age of 69 years.

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Objective: Our purpose was to establish the most frequent diagnoses associated with widespread ground-glass opacity on CT and to determine if the distribution of ground-glass opacity at a lobular level affects the likelihood of a given diagnosis.

Materials And Methods: A retrospective search of our department's CT database from January 1998 through December 2000 revealed 153 cases of ground-glass opacity. Patients evaluated using bronchoscopy or open biopsy within 30 days (mean, 6.

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The purpose of this study was to evaluate CT findings in nosocomial Pseudomonas aeruginosa Pneumonia (PAP) and to compare features of PAP in patients with isolated P. aeruginosa cultures and those with coexistent infections. A retrospective database search revealed 28 patients with nosocomial PAP (12 men, 16 women; mean age, 57 years) in which thoracic CT had been performed within a mean of 1.

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