Publications by authors named "Rosie Asher"
Cholinergic medication for antipsychotic-induced tardive dyskinesia.
Cochrane Database Syst Rev
March 2018
Article Synopsis
- Tardive dyskinesia (TD) is a side effect of conventional antipsychotic medications, possibly linked to a lack of cholinergic activity, and cholinergic drugs have been explored as a treatment option for it.
- This study aimed to evaluate the effectiveness of various cholinergic drugs in treating antipsychotic-induced TD in individuals with schizophrenia or other chronic mental health issues.
- A systematic search identified 14 controlled trials conducted from 1976 to 2014, comparing the effects of cholinergic medications to placebo among patients with TD.
Fluphenazine decanoate (depot) and enanthate for schizophrenia.
Cochrane Database Syst Rev
February 2015
Background: Intramuscular injections (depot preparations) offer an advantage over oral medication for treating schizophrenia by reducing poor compliance. The benefits gained by long-acting preparations, however, may be offset by a higher incidence of adverse effects.
Objectives: To assess the effects of fluphenazine decanoate and enanthate versus oral anti-psychotics and other depot neuroleptic preparations for individuals with schizophrenia in terms of clinical, social and economic outcomes.