Chronic Lymphocytic Thyroiditis with Oncocytic Metaplasia Influences PD-L1 Expression in Papillary Thyroid Carcinoma.

Background: Despite the increasing recognition of PD-L1 as predictor of immunotherapeutic response in various malignancies, its role and prognostic significance in thyroid cancer remain underexplored and subject to debate. This study begins to address this gap by comprehensively analyzing PD-L1 expression in papillary thyroid carcinoma (PTC) and investigating its correlation with key clinicopathological variables.

Methods: We conducted immunohistochemistry (IHC) to assess PD-L1 expression in whole-tissue sections from 121 primary papillary thyroid carcinoma (PTC) cases.

Follow-Up of Women with Cervical Cytological Abnormalities: Progression and Regression Events.

Abnormalities in the cervix, when identified early by Pap smear, can be treated in the early stages or in the precursor stages of the neoplasia, which may increase the chances of regression of the lesion. The aim to verify the rate of cervical abnormalities and to evaluate the risk of progression or regression associated with age and cytological diagnosis. Methods: The study was conducted in a referral hospital in Southern Brazil, based on the results of pathology and cytopathology laboratory tests of uterine cervix.

Impact of Her-2 Overexpression on Survival of Patients with Metastatic Breast Cancer.

Introduction: Breast cancer is a complex and heterogeneous disease which is increasingly important as a public health problem. In Brazil, 57,960 new cases have been estimated to be the burden in 2016 and 2017. Despite advances in early diagnosis and therapy, approximately 20-30% of patients, even with early stage lesions, will develop distant metastatic disease.

Impact of cell arrangement of pleural effusion in survival of patients with breast cancer.

Objective: This study was performed to evaluate the potential influence of cytological differences between pleural effusions on the survival of women with metastatic breast cancer during 30 months of follow-up.

Study Design: A hospital-based cohort study was performed. Pleural fluid cytology slides from patients with breast cancer were examined.

The role of urine cytology for 'decoy cells' as a screening tool in renal transplant recipients.

Objective: To determine the role of urine cytology for 'decoy cells' as a screening tool for polyomavirus type BK (BKV) infection in renal transplant recipients.

Study Design: This was a prospective cohort study of patients undergoing renal transplantation between 2006 and 2010.

Results: A total of 442 patients underwent urine cytology for decoy cells, 27.