Publications by authors named "Roshchevskaia I"

As a result of haemodynamic and structural changes occurring in athletes' heart under the influence of systematic physical loads, myocardial electrical activity changes that is reflected on the electric field being formed on the body surface. The heart electrical activity during ventricular depolarization at rest has been investigated in the highly skilled athletes who train to develop physical characteristics--endurance and strength by a method of electrocardiotopography. In the investigated sportsmen under uniformity of the character of the movement of positive and negative cardioelectric potential zones and localization of extrema, and general depolarization duration, the significant distinctions of: 1) amplitude of the maximum negative extremum, 2) the time of the beginning and end of the first inversion, 3) duration of the second inversion, the initial stage and the stability period between inversions, 4) the relative location of the zones of positive and negative cardiopotentials were revealed.

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The research of heart electrical activity of sportsmen-swimmers has been carried out using a functional test with physical activity. Standard 12-lead electrocardiograms and the cardioelectric field on the athletes' thorax surface were analyzed at rest and in every minute of a five-minute recovery period after submaximal workload. The changes of amplitude-temporal characteristics of the heart electric field on the athletes' body surface were revealed while performing physical workload.

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The article presents a literature review devoted to a description of electrical potentials of the fetus heart on the pregnant woman's abdomen using the model dipole generator. The main results of the model evaluation of the influence of extracardiac factors on the fetal ECG during pregnancy and of a choice of a preferable location of electrodes on the maternal abdomen are given. The fetal ECG models for evaluating signal filtering algorithms are described.

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By the method of multichannel synchronous cardioelectropotography, sequence of depolarization of intramural atrial layers was studied in representatives of ungulate animals--pigs. In the pig atrial myocardium there is revealed a complex picture of spreading of activation fronts, connected with non-uniform anatomical structure and subendocardial (intramural) disposition of area of initial activation. The general character of sequence of depolarization of the pig atrial myocardium is comparable with carnivores (dog) and even-toed (sheep) animals.

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The echocardiographic research of the left ventricular has revealed heterogeneity of thickness of the posterior wall and interventricular septum in three parallel planes in the transverse direction of the left ventricle in calves. The amplitude of systolic motion of the left ventricle posterior wall is larger than that of the interventricular septum at the level of the mitral valve, at the level of the papillary muscles, and at the apical level. The excursion of left ventricular walls in the basal level is twice as large as the mobility of ventricular walls in the apical level.

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The form and distribution of extracellular cardioelectric potentials and the sequence of the excitation wave propagation on epicardium of the pig atria were studied by the method of multichannel synchronous cardioelectrotopography. The studies have shown that in pig the excitation wave breaks on epicardium of the right atrium at the base of the upper vena cava. Negative initial atrial complexes are registered in this area.

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The working myocardium architecture was studied in heart ventricles of Wistar rats using the method of layer-by-layer dissection. Ventricle myocardium in the rat was found to be formed by three layers: superficial (subepicardial), middle and deep (subendocardial). The superficial and deep layers were present in both ventricles, while the middle one was found only in the left ventricle.

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The dynamics of potential distribution of cardiac electric field on the body surface was studied in renovascular hypertensive rats (Goldblatt type) during the ventricular activity. Three inversions of the mutual location of positive and negative areas of the cardiac electric field on the body surface were found in normotensive and hypertensive rats during the QRS-T period. Left ventricular hypertrophy of the heart in rats caused by renovascular hypertension results in changes of temporal and amplitude characteristics of the body surface potential distribution during the initial and terminal ventricular activity.

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Morphometric and functional parameters of the heart left ventricle in rabbits during systole and diastole were investigated by the method of echocardiography. Morphometric parameters were studied on three levels: the mitral valve, the papillary muscles and the apical level. The internal dimension of the left ventricle uniformly decreases in three parallel planes during systole, its maximal reduction being observed on the apical level.

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Architecture of the working myocardium fibers in pig cardiac ventricles was studied using the method of layer-by-layer splitting of muscle bundles. It was shown that the muscle fiber bundles in both ventricles were arranged in three directions. Three layers of fibers were distinguished as superficial, middle and deep.

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In anaesthetised rabbits at normal body temperature, the earliest ventricles' epicardial recovery occurs at the heart apex and adjacent left ventricle's surface whereas the latest one occurs at the epicardium of the right ventricle's base. A decrease in the mediastinum temperature to 32 degrees C reversed the recovery sequence. Following the cooling of the heart, the longest prolongation of the activation-recovery interval occurred at the heart apex area and the lowest one--at the right ventricle base.

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Parameters of cardioelectric field on body surface and propagation of excitation in ventricular myocardium during initial activation were studied using multichannel synchronous electrocardiotopography. It was shown that inversion of areas of negative and positive potentials of cardioelectric field on body surface at the moment of excitation propagation to the epicardium reflected changes in the main direction of excitation wavefront in ventricles.

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Electrical pacing of the apex, base, and free wall of the heart right and left ventricles, as well as the left ventricle's interventricular septum revealed that localisation of the ectopic focus determined the sequence of ventricular depolarisation, the site formation, and the pathway of displacement of the areas' positive and negative potentials and their extrema on the thoracic surface. Time of the mutual movement (inversion) of positive and negative zones on the body surface was found to depend on the pacing site in the wall of ventricles.

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Multifocal depolarisation of the pigeon ventricle's epicardium was revealed. A time inversion correlation was found between cardiac electrical field's positive and negative areas on the body surface and the multifocal depolarisation of the ventricle epicardium, during the period of initial ventricular activity.

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The depth of the myocardial wall ectopic focus was found to affect spatial and temporal characteristics of the depolarization process in the heart ventricular surface. Duration of the ventricular epicardial depolarization under the ectopic foci located in subendocardial and intramural layers of the myocardium was shorter than in epicardial stimulation of the ventricles. A dependence of the ectopic excitation duration on the pacing site localization in the epicardium, was revealed.

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