Influence of time of day and intermittent aerobic exercise on vascular endothelial function and plasma endothelin-1 in healthy adults.

Reduced flow-mediated dilation (FMD) and elevated plasma endothelin-1 (ET-1) levels may contribute to the higher incidence of adverse cardiovascular events observed in the morning hours. A single bout of intermittent exercise abolishes the diurnal variation in FMD. Studies examining the effects of exercise on vascular and plasma ET-1 responses at different times of day are lacking.

Inducible clindamycin resistance and genes in in school children in Kathmandu, Nepal.

Aim: Resistance to methicillin and Macrolide-Lincosamide and Streptogramins B and their association with genes in are unknown in Nepal.

Materials & Methods: Nonduplicate nasal swabs from 160 school children were collected from April to September 2018 and processed using standard microbiological procedures.

Results: Out of 160 samples, 64 (40%) were in which 17 (26.