Publications by authors named "Roshan Ravishankar"
Article Synopsis
- Filopodia are crucial for neuronal development, and proteins like TOCA-1 regulate their formation by interacting with actin and Ena/VASP proteins.
- Increasing TOCA-1 levels boosts Ena/VASP binding and correlates with enhanced filopodial growth in retinal ganglion cells.
- TOCA-1 clusters facilitate filopodial protrusion independently of membrane curvature, relying on its SH3 domain and activation of the Cdc42 protein.
Objective: To evaluate programmed death ligand 1 (PD-L1) staining fidelity between the primary tumor and associated lymph node metastases in bladder cancer. To secondarily evaluate whether neoadjuvant chemotherapy (NAC) affects this relationship.
Methods: Sixty-seven subjects with residual bladder cancer on cystectomy and associated positive lymph nodes were identified between 2008 and 2015.