Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF).

The development of breast cancer has been mainly reported in women who have reached the post-menopausal stage; therefore, it is the primary factor responsible for death amongst postmenopausal women. However, if treated on time it has shown a survival rate of 20 years in about two-thirds of women. Cases of breast cancer have also been reported in younger women and the leading cause in them is their lifestyle pattern or they may be carriers of high penetrance mutated genes.

Nanotechnology's Applications and Potential in Various Fields.

Since ancient times, several sorts of nanoparticles have been employed in the quickly expanding field of nanotechnology. These features include size, shape, and chemical as well as physical properties. Because of their small size and huge surface area, carbon-based nanoparticles, including fullerenes, carbon nanotubes, graphene, graphene oxide, and carbon-based quantum dots, have attracted a lot of attention in a variety of sectors, including biomedical applications.

Biochemical Abnormalities Associated With Sudden Infant Death Syndrome: A Case Report.

Sudden infant death is a complex event characterized by biochemical features that are difficult to understand in general settings. Herein, we present a case report of a three-month-old infant who succumbed to sudden infant death syndrome (SIDS), focusing on the biochemical abnormalities identified through post-mortem analysis. The infant, previously healthy and meeting developmental milestones, was found lifeless in the crib during sleep.

Is there a relationship between somatic sensations, impaired vision, and cognitive performance using the factor structure of the convergence insufficiency symptoms survey questionnaire?

Aims: This study aims to evaluate the relationship between somatic sensations, impaired vision, and cognitive performance using the factor structure convergence insufficiency symptoms survey questionnaire in university undergraduate and post-graduate students.

Settings And Design: Centre-based and questionnaire-based.

Subjects And Methods: Subjects were recruited from a university.

Symptoms 6 months following SARS-CoV-2 infection in Nepali women.

In Nepal, over 1 million individuals have tested positive for SARS-CoV-2. We sought to describe the frequency of nonrecovery from this infection at 6 months and associated symptoms. We conducted a retrospective cohort study of 6142 women who had positive and negative PCR tests for this infection 6 months previously at 3 institutions in Kathmandu.

Impact of Vaping on Lungs: An Indian Prospect.

Electronic cigarettes, or vape pens, have gained popularity among young people due to their attractive appearance, but they also have numerous side effects. These devices come in various shapes, sizes, and costs, with many brands and various flavors to choose from. As of now, there are around 2,807 people hospitalized in the United States due to vaping.

Music Therapy in the Treatment of Dementia: A Review Article.

The etiology of depression is the degeneration of the brain cells involved in cognitive function before the other brain cells. It is characterized by a neurological condition that causes a reduction in terms of physical, social, and cognitive impairment and has no cure presently. These nonpharmacological approaches, such as music therapy, enhance living outcomes for those dealing with dementia and also reduce behavioral incidence.

Portal Vein Variations, Clinical Correlation, and Embryological Explanation: A Review Article.

Portal vein (PV) is a large vein that collects blood from the abdominal part of gall bladder, pancreas, alimentary tract, and spleen and transports to the liver. One of the parts of the extraembryonic venous system, the vitelline veins, is where PV starts. In about five weeks of gestation, a venous plexus is formed, and variations in this plexus lead to portal variance.

Chronic Kidney Disease: Its Relationship With Obesity.

A significant obstacle to avoiding chronic illnesses in people worldwide is the increasing development of obesity. They are supported by economic expansion, mechanized transportation, a rise in sedentary behavior, and a switch from a wholesome, healthy diet to processed foods and high-calorie meals, including fast food and sugary drinks. Many developed or emerging countries have seen the prevalence of obesity in their populations increase twice over.

Limited influence of irrigation on pre-monsoon heat stress in the Indo-Gangetic Plain.

Hot extremes are anticipated to be more frequent and more intense under climate change, making the Indo-Gangetic Plain of India, with a 400 million population, vulnerable to heat stress. Recent studies suggest that irrigation has significant cooling and moistening effects over this region. While large-scale irrigation is prevalent in the Indo-Gangetic Plain during the two major cropping seasons, Kharif (Jun-Sep) and Rabi (Nov-Feb), hot extremes are reported in the pre-monsoon months (Apr-May) when irrigation activities are minimal.

Meningeal Signs and Cerebellar Involvement in Scrub Typhus: A Case Report.

Scrub typhus is an arthropod-borne fever that follows the bite of the larval form of Leptotrombidium mite carrying . It remains a serious health problem in the Asia-Pacific region. While it commonly presents as an undifferentiated fever with chills and an eschar, complications like pneumonitis, acute respiratory distress syndrome, disseminated intravascular coagulation, and meningoencephalitis may cause scrub typhus to be fatal.

Prevalence of Cardiovascular Risk Factors in Apparently Healthy Urban Adult Population of Kathmandu.

Background: Cardiovascular diseases account for most deaths and major proportion of disabilities worldwide. Major cardiovascular risk factors are implicated in almost 75% of cardiovascular diseases. There has been a rapid increase in prevalence of such risk factors in apparently healthy young adults of urban population.

Prevalence and Clinical Spectrum of Liver Disease in Nepalese HIV-Sero-Positive Patients Undergoing Antiretroviral Therapy: A Cross-Sectional Hospital Based Study.

Introduction: Liver enzyme abnormalities are common in HIV patients, and the prevalence varies across the nations. In Nepal, however, prevalence of liver enzyme disorder and the spectrum of these populations are lacking.

Objective: The present study sheds light on prevalence and clinical spectrum of liver disease in Nepalese HIV-sero-positive patients.

Data on optimization of expression and purification of AIMP2-DX2 protein in .

AIMP2-DX2 is a splicing variant of AIMP2 protein which has been implicated in human lung cancer and chemoresistance of ovarian cancer (J.W. Choi, D.

Purification and biophysical characterization of the AIMP2-DX2 protein.

Besides their primary role in protein synthesis, aminoacyl-tRNA synthetases (AARSs) are involved in several non-canonical processes such as apoptosis, inflammation and angiogenesis through their interactions with various cellular proteins. Nine of these AARSs interact with three aminoacyl-tRNA synthetase interacting multifunctional proteins (AIMPs), forming a multi-synthetase complex (MSC) in eukaryotes. Among the three AIMPs, AIMP2 is involved in controlling cell proliferation and apoptosis.