: The Uncanny, sexuality, and trauma.

Here the author draws on Theodor Fontane's 1895 novel to consider the links between Freud's paper "The Uncanny" and his elaboration of the trauma of sexuality and the après-coup. Conceptualizing trauma in contemporary clinical theory inevitably draws on the theory of the après-coup: the blow that is inflicted on the psyche when the impact of the early event is retranscribed at a later date. The author considers the trauma that Effi experiences, not the catastrophic trauma of death or assault but the deceptive trauma, is disguised as an unparalleled opportunity for Effi.

Measuring outcomes in trials of interventions for people who self-harm: qualitative study of service users' views.

Background: Patients often have very different ideas from clinicians about what they want treatments to achieve. Their views on what outcomes are important are not always reflected in trials.

Aims: To elicit the views of people who self-harm on the most commonly used outcome measures and to identify the outcomes that matter to them.

Assessing fugitive emissions of CH from high-pressure gas pipelines in the UK.

Natural gas pipelines are an important source of fugitive methane emissions in lifecycle greenhouse gas assessments but limited monitoring has taken place of UK pipelines to quantify fugitive emissions. This study investigated methane emissions from the UK high-pressure pipeline system (National Transmission System - NTS) for natural gas pipelines. Mobile surveys of CH emissions were conducted across four areas in the UK, with routes bisecting high-pressure pipelines (with a maximum operating pressure of 85bar) and separate control routes away from the pipelines.

What's in a "research passport"? A collaborative autoethnography of institutional approvals in public involvement in research.

Plain English Summary: The article analyses the process of securing permissions for members of the public (we refer to them as "research partners") and academics involved in a qualitative study of public involvement in research (PIR) across eight health sciences projects in England and Wales. All researchers, including research partners, need to obtain a "research passport" from UK NHS trusts where they intend to carry out research. The article presents the experiences and observations of the authors, who all went through the process.

Effective support for those who are "hard to engage": a qualitative user-led study.

Background: Up to 30% of people with mental health problems drop out of contact with mental health services with negative implications for continuity of care. Services with an assertive outreach approach aim to sustain engagement.

Aims: This study explored the perceptions and needs of people often described as "hard to engage" in order to understand more about how services can best support them.

Anxiety: the importunate companion. Psychoanalytic theory of castration and separation anxieties and implications for clinical technique.

In this article I consider the implications of our differing psychoanalytic theories of anxiety on clinical technique. Drawing on differentiations between the focus on separation or castration anxiety and the relative neglect of the latter in contemporary writing, I look in detail at two clinical examples of psychoanalysis in borderline young adults to exemplify the issue.(1).

Muscle damage alters the metabolic response to dynamic exercise in humans: a 31P-MRS study.

We used ³¹P-magnetic resonance spectroscopy to test the hypothesis that exercise-induced muscle damage (EIMD) alters the muscle metabolic response to dynamic exercise, and that this contributes to the observed reduction in exercise tolerance following EIMD in humans. Ten healthy, physically active men performed incremental knee extensor exercise inside the bore of a whole body 1.5-T superconducting magnet before (pre) and 48 h after (post) performing 100 squats with a load corresponding to 70% of body mass.

Eccentric exercise-induced muscle damage dissociates the lactate and gas exchange thresholds.

We tested the hypothesis that exercise-induced muscle damage would increase the ventilatory (V(E)) response to incremental/ramp cycle exercise (lower the gas exchange threshold) without altering the blood lactate profile, thereby dissociating the gas exchange and lactate thresholds. Ten physically active men completed maximal incremental cycle tests before (pre) and 48 h after (post) performing eccentric exercise comprising 100 squats. Pulmonary gas exchange was measured breath-by-breath and fingertip blood sampled at 1-min intervals for determination of blood lactate concentration.

Effect of exercise-induced muscle damage on ventilatory and perceived exertion responses to moderate and severe intensity cycle exercise.

This study examined the effect of exercise-induced muscle damage (EIMD) on ventilatory and perceived exertion responses to cycle exercise. Ten healthy, physically active men cycled for 6 min at moderate intensity and to exhaustion at severe intensity before and 48 h after eccentric exercise (100 squats with a load corresponding to 70% of body mass). Changes in ventilation and ratings of perceived exertion (RPE) were calculated for each individual and expressed against time (moderate and severe exercise) and as a percentage of time to exhaustion (severe exercise).

Effect of eccentric exercise-induced muscle damage on the dynamics of muscle oxygenation and pulmonary oxygen uptake.

Unaccustomed eccentric exercise has a profound impact on muscle structure and function. However, it is not known whether associated microvascular dysfunction disrupts the matching of O2 delivery (Qo2) to O2 utilization (Vo2). Near-infrared spectroscopy (NIRS) was used to test the hypothesis that eccentric exercise-induced muscle damage would elevate the muscle Qo2:Vo2 ratio during severe-intensity exercise while preserving the speed of the Vo2 kinetics at exercise onset.