Risk of prostate cancer after detection of isolated high-grade prostatic intraepithelial neoplasia (HGPIN) on extended core needle biopsy: a UK hospital experience.

Background: High-grade prostatic intraepithelial neoplasia (HGPIN) is a precursor lesion to prostate cancer (CaP). UK-based studies examining the occurrence of isolated HGPIN and subsequent risk of CaP are lacking. Our aim was to assess the occurrence of HGPIN in a regional UK population and to determine whether in a retrievable cohort of such patients that had repeat extended core biopsies, there was an elevated risk of CaP.

The economic and workload impact of 'backdoor' prostate-specific antigen screening on the UK National Health Service: a single-centre experience.

Objective: To determine the economic burden and additional cost on one hospital within the UK National Health Service secondary to prostate-specific antigen screening by a private recruitment company for a clinical drug trial.

Patients And Methods: Data were reviewed from all patients who were excluded from the trial and referred across by the recruitment company between May 2004 and April 2005. The additional cost for all their investigation and treatment was calculated.

Is DRE essential for the follow up of prostate cancer patients? A prospective audit of 194 patients.

Background: Prostate cancer follow up forms a substantial part of the urology outpatient workload. Nurse led prostate cancer follow up clinics are becoming more common. Routine follow-up may involve performing DRE, which may require training.