Identification of Risk Factors for Initial Elevated Vancomyin Trough Concentrations.

Recent literature suggests that elevated vancomycin trough concentrations (>20 µg/mL) may be associated with an increased risk of nephrotoxicity and lead to an increase in mortality and hospital length of stay. The purpose of this study was to identify variables that may be predictive of elevated initial vancomycin trough concentrations. Retrospective case-control study of all adult patients who had an initial vancomycin trough concentration measured between January 1, 2013, and December 31, 2014.