Publications by authors named "RoseMary Beitia"
Objectives: Management of eosinophilic esophagitis (EoE) requires repeated endoscopic mucosal sampling to assess disease activity. A less invasive and expensive means of monitoring of EoE is required. The objective of this study was to assess the accuracy, safety, and tolerability of the cytosponge compared to endoscopy and biopsy for histologic assessment of EoE.
View Article and Find Full Text PDFObjective: Eosinophilic esophagitis (EoE) can be difficult to diagnose. We aimed to evaluate whether a gene expression score could differentiate adult EoE cases from non-EoE controls and to determine whether scores normalized after treatment for EoE.
Methods: We analyzed prospectively collected esophageal biopsies from EoE patients (diagnosed as per consensus guidelines and after a proton pump inhibitor trial) and non-EoE controls.
Background: Because eosinophilic esophagitis (EoE) causes dysphagia, esophageal narrowing, and strictures, it could result in low body mass index (BMI), but there are few data assessing this.
Aim: To determine whether EoE is associated with decreased BMI.
Methods: We conducted a prospective study at the University of North Carolina from 2009 to 2013 enrolling consecutive adults undergoing outpatient EGD.
Background & Aims: Little is known about the diagnostic utility of the Eosinophilic Esophagitis (EoE) Endoscopic Reference Score (EREFS), and how scores change in response to treatment. We investigated the operating characteristics of the EREFS in diagnosis of EoE, how the score changes with treatment, and ways to optimize scoring system.
Methods: We performed a prospective study of adults undergoing outpatient upper endoscopy from August 2011 through December 2013 at the North Carolina School of Medicine.
Article Synopsis
- This study aimed to differentiate eosinophilic esophagitis (EoE) from gastroesophageal reflux disease (GERD) and dysphagia by assessing clinical and endoscopic features without esophageal biopsies.
- A total of 81 EoE cases and 144 controls were analyzed, with a predictive model showing high accuracy (AUC of 0.944) based on key features like age, sex, dysphagia, and specific endoscopic findings.
- The findings suggest that using these clinical and endoscopic predictors can effectively identify individuals at low risk for EoE, potentially reducing the need for costly and invasive biopsy procedures.
Objectives: Noninvasive biomarkers would be valuable for diagnosis and monitoring of eosinophilic esophagitis (EoE). The aim of this study was to determine the utility of a panel of serum biomarkers for the diagnosis and management of EoE.
Methods: We conducted a prospective cohort study of consecutive adults undergoing outpatient esophagogastroduodenoscopy.