Publications by authors named "Rose-Pittet L"

Initial signs of malignant lymphoma are rarely due to bone lesions. We reviewed 6 cases with early skeletal involvement, recently observed in the rheumatology and hematology departments. In 3 patients, magnetic resonance imaging (MRI) was added to traditional investigations, including radiography, radionuclide bone scan and computerized tomography.

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The authors report an uncommon soft tissue tumor, a diffuse giant cell tumor of tendon sheath. The location is uncommon too, the ankle, behind tibial shaft and forward achilleus tendon. The primary diagnosis of ankle and leg lymphoedema, has been for a long time.

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Bone localizations revealing Hodgkin's disease or non-Hodgkin's malignant lymphoma, are unusual. We are reporting 11 recent cases collected in rheumatology and haematology departments, including 4 where a comprehensive study of X-rays, scintigrams, axial tomograms and nuclear magnetic resonance imaging was performed. Review of the literature as well as our experience concerning the type of onset of the bone involvement, the clinical correlation, the imaging techniques, have led us to consider nuclear magnetic resonance as a decisive factor which should be offered at an early stage in the diagnostic approach.

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Seven patients with arrhythmogenic right ventricular dysplasia were explored by magnetic resonance imaging (MRI), using the spin-echo technique (TR = the patient's own RR cycle; TE = 28 ms, 56 ms, 84 ms) with multiple, contiguous, 7 to 10 mm thick sections performed in two planes: axial plus sagittal or frontal planes. In 5 out of 7 patients, MRI showed dysplastic lesions in the right ventricular wall presenting typically as fat-like high signals contrasting with the normal myocardium. In 2 patients, no lesion was clearly visualized.

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This study concerns the investigation of 32 soft-tissue tumors by MRI, subsequently verified by biopsies or surgery (n = 28) or other investigations (n = 4). MRI can suggest the diagnosis in some cases: lipomas cysts, hematomas, neuromas, desmoid tumors, hemangiomas, by contrast analysis and morphologic aspects; sometimes, malignant lesions are suspected on particular anatomic criteria. MRI is excellent in the evaluation of local extension.

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The authors report a prospective study of eighty-five patients with suspected meniscal or ligament lesions examined using Magnetic Resonance Imaging (MRI). In all cases, the results were compared with the findings at arthroscopy. The technique seems to be a good non-invasive diagnostic procedure, whose accuracy is 87 p.

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Two further cases of aseptic osteonecrosis of femoral head during pregnancy are reported, and the literature reviewed of this rare etiology of debatable etiopathogenicity. The value of MR imaging is demonstrated both for early positive diagnosis and for the differential diagnosis from decalcifying algodystrophy.

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Results of magnetic resonance imaging of 37 cases of lesions of meniscus and ligaments of knee are reported and compared with arthroscopy findings. Use of MRI appears to be an excellent non-invasive diagnostic method, with current major indications in acute knee injuries and for evaluation of chronic laxity. It also allows guidance of surgical procedures.

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Article Synopsis
  • A study analyzed 50 cases of mediastinal gland invasion from primary bronchial cancer using CT scans, NMR imaging, and mediastinoscopy, highlighting imaging methods' effectiveness.
  • Axial mediastinoscopy proved to be the most reliable with a sensitivity of 93%, outperforming both NMR (80% sensitivity) and CT (70% sensitivity), although CT had higher specificity (83%) compared to NMR (70%).
  • The findings recommend using combined CT scan and mediastinoscopy for preoperative assessment, particularly suggesting anterolateral mediastinoscopy for diagnosing enlarged anterior mediastinal lymphatic chains.
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This correlative study concerns the investigation of 22 mediastinal tumors by MRI and CT, subsequently verified by biopsies or surgery. It allows us to better define the technical aspects in the realization of MRI, including an assessment of the use of ECG gating. It also permits an appreciation of the respective performances of these 2 imaging methods: there is a good correlation between the two technics for both the positive and etiologic diagnosis of mediastinal tumors: in etiologic diagnosis, the same limitations were encountered with the two technics.

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Three patients with straight azygos vein continuation of inferior vena cava (IVC) were studied by nuclear magnetic resonance (NMR) imaging. In all three cases the diagnosis had been established previously by ultrasound and/or computed tomography imaging, but NMR images provided better anatomical precision of the venous anomaly : visualization of the total trajectory of the major azygos vein, the caliber of which can exceed that of aorta, and absence of retrohepatic segment of IVC but presence of a short supradiaphragmatic segment towards which converge the suprahepatic veins; anastomotic etwork between IVC and major azygos vein contributing to ensure continuity of venous drainage superior to its renal segment. The advantages of NMR are described and the precise diagnostic role of this new method of imaging in the diagnosis of this type of anomaly discussed.

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Results of nuclear magnetic resonance exploration in a patient with chronic thrombosis of main pulmonary arteries are used to outline an elementary semiology in agreement with current documented data. Signs observed relate to the thrombosis and showing of flow due to associated pulmonary artery hypertension. Cardiac synchronization is essential: obtaining 2 echos by the spin-echo technique allows differentiation of circulatory slowing phenomena, which provoke increased strength of 2nd echo, from the thrombus itself.

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Computed tomography imaging in a patient with a pericardial effusion showed fluid collection in the superior recessus of pericardium confirmed by mediastinoscopy. Topographic and morphologic criteria and anatomic bases of the radiologic diagnosis are described, and emphasis placed on the fact that because of density variations in pericardial effusions the latter has to be added to the already long list of abnormal opacities of Barety's space.

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Varicella pneumonia, is commonly an easy diagnostic because of specific eruption. We report a case in an 8 years old child with moderately with-spread macular and purpuric rash. Hematologic data showed anemia and thrombocytopenia from central origin.

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