A national study of the association between traffic-related air pollution and adverse pregnancy outcomes in Canada, 1999-2008.

Numerous studies have examined the association of air pollution with preterm birth and birth weight outcomes. Traffic-related air pollution has also increasingly been identified as an important contributor to adverse health effects of air pollution. We employed a national nitrogen dioxide (NO2) exposure model to examine the association between NO2 and pregnancy outcomes in Canada between 1999 and 2008.

Associations of Pregnancy Outcomes and PM2.5 in a National Canadian Study.

Background: Numerous studies have examined associations between air pollution and pregnancy outcomes, but most have been restricted to urban populations living near monitors.

Objectives: We examined the association between pregnancy outcomes and fine particulate matter in a large national study including urban and rural areas.

Methods: Analyses were based on approximately 3 million singleton live births in Canada between 1999 and 2008.