Publications by authors named "Rose K Sia"

Article Synopsis
  • This study evaluated the effects of LASIK, PRK, and SMILE surgeries on patient-reported outcomes among active-duty U.S. Military Servicemembers, focusing on vision quality and satisfaction before and after surgery.
  • A total of 375 Servicemembers underwent these procedures, with results showing that 94-95% achieved 20/20 vision or better, with significant improvements in far vision for LASIK and PRK specifically.
  • Overall, all three surgical options provided excellent visual outcomes and minimal side effects, enhancing daily activities for the Servicemembers six months post-operation.
View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to compare the early visual quality, specifically low contrast acuity (LCVA), between two types of eye surgery: SMILE and LASIK.
  • The analysis involved military personnel who underwent either SMILE or two types of LASIK (wavefront-guided and wavefront-optimized), evaluating their night vision and LCVA up to three months after surgery.
  • Results showed that LASIK patients had better night vision and photopic LCVA at one month compared to SMILE patients, while WFO LASIK had mixed results at three months, indicating that LASIK might lead to faster recovery of visual quality than SMILE.
View Article and Find Full Text PDF

Background And Objective: The goal of this study was to determine the anatomic outcome of traumatic retinal detachment (RD) from combat ocular trauma.

Materials And Methods: Retrospective study of patients sustaining a traumatic RD in Operation Iraqi Freedom and Operation Enduring Freedom who were evacuated to Walter Reed Army Medical Center from 2001 to 2011. The Fisher exact test, Wilcoxon rank sum test, and Agresti and Coull methods were used for analyses.

View Article and Find Full Text PDF

Introduction: Traumatic brain injury (TBI) remains a significant source of disability for active duty service members in both deployed and training settings as well as those who have left active service. Service members with ocular trauma are at risk for a TBI and should be screened appropriately. Early detection results in treatment to minimize long-term sequelae which can often be debilitating.

View Article and Find Full Text PDF

Purpose: The purpose of this study was to assess visual and health-related quality of life (QOL) among U.S. military service members who sustained combat ocular trauma (COT) with or without associated traumatic brain injury (TBI).

View Article and Find Full Text PDF

Purpose: To assess early visual outcomes and military task performance after small-incision lenticule extraction (SMILE) among U.S. military service members.

View Article and Find Full Text PDF

 The aim of this study was to evaluate whether the simulated tissue models may be used in place of animal-based model for corneal laceration repair for surgical skills acquisition.  Prospective randomized controlled trial.  Seventy-nine military and civilian 2nd- and 3rd-year ophthalmology residents and 16 staff ophthalmologists participating in the Tri-Service Ocular Trauma Skills Laboratory at the Uniformed Services University (Bethesda, MD).

View Article and Find Full Text PDF

Lipids in complex, protein-enriched films at air/liquid interfaces reduce surface tension. In the absence of this benefit, the light refracting and immunoprotective tear film on eyes would collapse. Premature collapse, coupled with chronic inflammation compromising visual acuity, is a hallmark of dry eye disease affecting 7 to 10% of individuals worldwide.

View Article and Find Full Text PDF

Purpose: To assess whether densitometry analysis appropriately monitors the development of haze in myopic patients after photorefractive keratectomy (PRK) when compared to subjective slit-lamp haze grade examinations, and whether sutureless cryo-preserved amniotic membrane reduced postoperative haze development when compared to the standard bandage contact lens.

Methods: In this retrospective cohort at the Center for Refractive Surgery, Walter Reed National Military Medical Center, a secondary analysis of prospectively collected data was performed. In the prospective study, participants underwent PRK for myopia.

View Article and Find Full Text PDF

Purpose: To assess the visual outcomes of small-incision lenticule extraction (SMILE) after the first year of treatments at a military refractive surgery center and compare with photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) outcomes during the same period.

Setting: Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir, VA.

Design: Retrospective study.

View Article and Find Full Text PDF

Background: This study evaluated the VIsion PERformance (VIPER) simulator's ability to assess the functional visual performance in warfighters conducting civilian and military tasks.

Methods: Thirty service members, aged 25-35 years old with a best corrected distance visual acuity (VA) better than or equal to 20/20 or logarithm of the minimum angle of resolution (logMAR) 0.00, were randomized to locate and identify road signs and mock improvised explosive devices (IEDs) under either daytime conditions or with infrared imagery, with (cc) and without (sc) wearing their habitual correction.

View Article and Find Full Text PDF

Purpose: To assess vision-related quality of life and military readiness and capabilities among active duty U.S. military service members undergoing refractive surgery.

View Article and Find Full Text PDF

Purpose: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery.

Methods: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7.

View Article and Find Full Text PDF

Objectives: To describe the visual outlook and quality of life of service members after combat ocular trauma.

Methods: In a single-center, prospective observational study of service members sustaining ocular trauma, participants underwent a series of ocular examinations and noninvasive tests, including the National Eye Institute Visual Functioning Questionnaire (VFQ-25).

Results: Of the 165 enrolled participants, 137 completed the VFQ-25.

View Article and Find Full Text PDF

Purpose: To compare visual performance, marksmanship performance, and threshold target identification following wavefront-guided (WFG) versus wavefront-optimized (WFO) photorefractive keratectomy (PRK).

Methods: In this prospective, randomized clinical trial, active duty U.S.

View Article and Find Full Text PDF

Purpose: To determine whether patients without dry eye preoperatively have an altered conjunctival goblet cell density and mucin secretion postoperatively and to explore what factors affect changes in goblet cell density and mucin secretion.

Setting: The former Walter Reed Army Medical Center, Washington, DC, USA.

Design: Prospective nonrandomized clinical study.

View Article and Find Full Text PDF

Purpose: To evaluate the effect of sutureless cryopreserved amniotic membrane (Prokera) on corneal wound healing after photorefractive keratectomy (PRK).

Setting: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA.

Design: Prospective nonrandomized control trial.

View Article and Find Full Text PDF

Background: Retreatments are sometimes necessary to correct residual or induced refractive errors following refractive surgery. Many different combinations of primary treatment methods and retreatment techniques have been studied, however, few studies have investigated wavefront-optimized (WFO) technology for retreatment following primary refractive surgery. This study aimed to report the outcomes of WFO photorefractive keratectomy (PRK) retreatments of refractive error following previous laser refractive surgery with PRK, laser in situ keratomileusis (LASIK), or laser-assisted subepithelial keratectomy (LASEK).

View Article and Find Full Text PDF

Purpose: To evaluate dry-eye manifestations after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) and determine the incidence and predictive factors of chronic dry eye using a set of dry-eye criteria.

Setting: Walter Reed Army Medical Center, Washington, DC, USA.

Design: Prospective, non-randomized clinical study.

View Article and Find Full Text PDF

Purpose: To compare visual outcomes following Visx Star S4 Customvue wavefront-guided and Allegretto Wave Eye-Q 400 Hz wavefront-optimized photorefractive keratectomy (PRK).

Setting: Warfighter Refractive Eye Surgery Program and Research Center, Fort Belvoir, Virginia, and Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

Design: Prospective randomized clinical trial.

View Article and Find Full Text PDF

Antimicrobial peptides are important as the first line of innate defense, through their tendency to disrupt bacterial membranes or intracellular pathways and potentially as the next generation of antibiotics. How they protect wet epithelia is not entirely clear, with most individually inactive under physiological conditions and many preferentially targeting Gram-positive bacteria. Tears covering the surface of the eye are bactericidal for Gram-positive and -negative bacteria.

View Article and Find Full Text PDF

Purpose: To compare visual outcomes following photorefractive keratectomy (PRK), PRK with mitomycin C (MMC-PRK), and LASEK in moderate and high myopia in military personnel.

Methods: This prospective, randomized contralateral eye study included 167 patients 21 years or older with manifest spherical equivalent -5.99 ± 1.

View Article and Find Full Text PDF

Purpose: To determine the association of single nucleotide polymorphisms (SNPs) of the thrombospondin 1 (THBS1) gene with development of chronic ocular surface inflammation (keratoconjunctivitis) after refractive surgery.

Design: Retrospective cohort study.

Participants: Active duty U.

View Article and Find Full Text PDF